Anti-STAM2 Rabbit pAb servicebio GB113020-100

$50.00
In stock
SKU
GB113020-100

 

Product Information

Protein full nameSignal transducing adapter molecule 2
SynonymsSTAM-2, Hrs-binding protein, Stam2, Hbp, STAM2A, STAM2B, HSE1 homolog
Uniprot IDO88811
ImmunogenRecombinant protein corresponding to Mouse STAM2
IsotypeIgG
Predicted MW./Observed MW.57 kDa / 70 kDa
PurityAffinity purification

Applications

Applications: WBSpecies: Mouse
Dilution: 1: 1000-1: 2000Positive Tissue: stomach, liver

Background

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

Images

WB analysis of STAM2(GB113020). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 2000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

Storage

StorageStore at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

 

 

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