Anti-CD38 Antibody, Rabbit Polyclonal sinobiological 10818-T58

$243.00
In stock
SKU
10818-T58
Catalog No.SizePrice (USD)
10818-T58-100100 µL$251.64

General Information

Product nameAnti-CD38 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD38
ImmunogenRecombinant Human CD38 Protein (Catalog#10818-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human CD38 (rh CD38; Catalog#10818-H08H; NP_001766.2; Val43-Ile300). CD38 specific IgG was purified by Human CD38 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ADPRC 1 Antibody; Anti-ADPRC1 Antibody; Anti-cADPR1 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-CD38 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HuT-78 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:38 kDa
Image 1 Alt TextHuman CD38 Western blot (WB) 36663
Image 1 URLSource image
Image 2 DescriptionAnti-CD38 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HuT-78 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:38 kDa
Image 2 Alt TextHuman CD38 Immunohistochemistry(IHC) 36664
Image 2 URLSource image
Image 3 DescriptionAnti-CD38 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HuT-78 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:38 kDa
Image 3 Alt TextHuman CD38 Immunofluorescence(IF) 36665
Image 3 URLSource image

Background Information

Full NameCD38 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4 , CD8 , B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.
Research Areas
  • Cancer Drug Targets
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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