Human ALK-1 ELISA Kit sinobiological KIT10066

$714.00
In stock
SKU
KIT10066
Catalog No.SizePrice (USD)
KIT10066-11 Kit (96 Tests)$740.55

General Information

Product nameHuman ALK-1 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural human ALK1.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity8.98 pg/mL
Assay range31.25-2000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Sample Dilution Buffer Concentrate 7. Color Reagent A 8. Color Reagent B 9. Stop Solution
Product overviewThis Human ALK-1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human ALK-1 protein in Serum . It contains recombinant Human ALK-1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of TGFB1、INHBA、TGFBR1、ACVR1、FKBP1A、TSC22D1、HSP90AA1、BAMBI、ENG and TGFB2 at 20 ng/mL in a mid-range recombinant human ALK1 control were assayed for interference. No significant interference was observed.

Synonyms: ACVRLK1 ELISA Kit, Human; ALK-1 ELISA Kit, Human; ALK1 ELISA Kit, Human; HHT ELISA Kit, Human; HHT2 ELISA Kit, Human; ORW2 ELISA Kit, Human; SKR3 ELISA Kit, Human; TSR-I ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman ALK-1/ACVRL1 ELISA Kit Standard Curve 33
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman ALK-1/ACVRL1 ELISA Kit Specificity 254
Image 2 URLSource image

Background Information

Full Nameactivin A receptor type II-like 1
DescriptionActivin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.
References
  1. French Rendu-Osler network, et al. (2004) Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France. Hum Mutat. 23(4): 289-299.
  2. Simon M, et al. (2006) Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system. J Neurosurg. 104(6): 945-9.
  3. Argyriou L, et al. (2006) Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia. Int J Mol Med. 17(4):655-9.

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