Anti-FGF-4 Antibody, Rabbit Polyclonal sinobiological 16043-T08
$243.00
In stock
SKU
16043-T08
| Catalog No. | Size | Price (USD) |
| 16043-T08-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-FGF-4 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FGF-4 |
| Immunogen | Recombinant Human FGF-4 Protein (Catalog#16043-HNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human FGF-4 (rh FGF-4; Catalog#16043-HNAE; NP_001998.1; Ser54-Leu206). FGF-4 specific IgG was purified by Human FGF-4 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-FGF-4 Antibody; Anti-HBGF-4 Antibody; Anti-HST Antibody; Anti-HST-1 Antibody; Anti-HSTF-1 Antibody; Anti-HSTF1 Antibody; Anti-K-FGF Antibody; Anti-KFGF Antibody; Anti-KS3 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human FGF-4 in human breast carcinoma with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human FGF-4 Immunohistochemistry(IHC) 42644 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human FGF-4 in human breast carcinoma with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human FGF-4 Immunohistochemistry(IHC) 42645 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining of human FGF-4 in human breast carcinoma with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 3 Alt Text | Human FGF-4 Immunohistochemistry(IHC) 42646 |
| Image 3 URL | Source image |
Background Information
| Full Name | fibroblast growth factor 4 |
| Description | FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) and extracellular signal-related kinase 1/2 (ERK1/2). Fibroblast Growth Factor 4 (FGF-4) could not only increase the proliferation of bone marrow mesenchymal stem cells (BMSCs), but also induce BMSCs into hepatocyte-like cells in vitro. FGF4 transduced BMSCs contributed to liver regeneration might by the transplanted microenvironment. The FGF4-bFGF BMSCs thus can enhance the survival of the transplanted cells, diminish myocardial fibrosis, promote myocardial angiogenesis, and improve cardiac functions. |
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