Human C1 inhibitor/C1-INH ELISA Kit sinobiological KIT10995
$714.00
In stock
SKU
KIT10995
| Catalog No. | Size | Price (USD) |
| KIT10995-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human C1 inhibitor/C1-INH ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human SerpinG1. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 27.4 pg/mL |
| Assay range | 125-8000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human C1 inhibitor/C1-INH ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human C1 inhibitor/C1-INH protein in Serum . It contains recombinant Human C1 inhibitor/C1-INH, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: C1-INH ELISA Kit, Human; C1IN ELISA Kit, Human; C1INH ELISA Kit, Human; C1NH ELISA Kit, Human; HAE1 ELISA Kit, Human; HAE2 ELISA Kit, Human; SERPING1 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human C1 inhibitor/SerpinG1 ELISA Kit Standard Curve 93 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human C1 inhibitor/SerpinG1 ELISA Kit Specificity 196 |
| Image 2 URL | Source image |
Background Information
| Full Name | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| Description | Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass. |
| References |
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