Mouse Endoglin/CD105 ELISA Kit sinobiological KIT50407
$400.00
In stock
SKU
KIT50407
| Catalog No. | Size | Price (USD) |
| KIT50407-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Mouse Endoglin/CD105 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Mouse ENG. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 4.4 pg/mL |
| Assay range | 12.5-800 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Mouse Endoglin/CD105 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse Endoglin/CD105 protein in Serum . It contains recombinant Mouse Endoglin/CD105, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of Mouse ACVR2B at 8 ng/mL in a mid-range recombinant Mouse ENG control were assayed for interference. No significant interference was observed. |
Synonyms: CD105 ELISA Kit, Mouse; Edg ELISA Kit, Mouse; Endo ELISA Kit, Mouse; Eng ELISA Kit, Mouse; S-endoglin ELISA Kit, Mouse
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Mouse Endoglin/CD105 ELISA Kit Standard Curve 132 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Mouse Endoglin/CD105 ELISA Kit Specificity 183 |
| Image 2 URL | Source image |
Background Information
| Full Name | endoglin |
| Description | Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD tripeptide which is a key recognition structure in cellular adhesion,,suggesting a critical role for endoglin in the binding of endothelial cells to integrins and/or other RGD receptors. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. As an accessory receptor for the TGF-β superfamily ligands, endoglin binds TGF-β1 and TGF-β3 with high affinity not by itself but by associating with TGF-β type II receptor (TβRII) and activates the downstream signal pathways. In addition, in human umbilical vein endothelial cells, ALK-1 is also a receptor kinase for endoglin threonine phosphorylation, and mutations in either of the two genes result in the autosomal-dominant vascular dysplasia, hereditary hemorrhagic telangiectasia (HHT). Endoglin has been regarded as a powerful biomarker of neovascularization, and is associated with several solid tumor types. |
| Research Areas |
|
| References |
|
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
