Human Erythropoietin R/EPOR ELISA Kit sinobiological KIT10707

$714.00
In stock
SKU
KIT10707
Catalog No.SizePrice (USD)
KIT10707-11 Kit (96 Tests)$740.55

General Information

Product nameHuman Erythropoietin R/EPOR ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human EPOR.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum,Lysate
Sensitivity4.8 pg/mL
Assay range9.38-600 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human Erythropoietin R/EPOR ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Erythropoietin R/EPOR protein in Serum,Lysate . It contains recombinant Human Erythropoietin R/EPOR, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of human EPO at 100 ng/mL in a mid-range recombinant human EPOR control were assayed for interference. No significant interference was observed.

Synonyms: EPO-R ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman EPOR/Erythropoietin Receptor ELISA Kit Standard Curve 14
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman EPOR/Erythropoietin Receptor ELISA Kit Specificity 224
Image 2 URLSource image

Background Information

Full Nameerythropoietin receptor
DescriptionErythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
References
  1. Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
  2. Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
  3. Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.

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