Anti-CHN1 Antibody, Rabbit Polyclonal sinobiological 14914-RP01

$143.00
In stock
SKU
14914-RP01
Catalog No.SizePrice (USD)
14914-RP01-100100 µL$147.96
14914-RP01-200200 µL$251.64
14914-RP01-400400 µL$355.32

General Information

Product nameAnti-CHN1 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CHN1
ImmunogenRecombinant Human CHN1 / chimerin 1 Protein (Catalog#14914-HNCB)
PreparationProduced in rabbits immunized with purified, recombinant Human CHN1 / chimerin 1 (rh CHN1 / chimerin 1; Catalog#14914-HNCB; NP_001813.1; Ala2-Phe459). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ARHGAP2 Antibody; Anti-CHN Antibody; Anti-DURS2 Antibody; Anti-n-chimerin Antibody; Anti-NC Antibody; Anti-RHOGAP2 Antibody

Background Information

Full Namechimerin 1
DescriptionCHN1, also known as chimerin 1, is a TPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. CHN1 is involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. The CHN1 gene provides instructions for making two very similar proteins called α1-chimaerin and α2-chimaerin. These proteins play an important role in the early development of the nervous system. In particular, they help regulate complex chemical signaling pathways during the formation and development of nerve cells (neurons). These proteins help guide the growth of axons and dendrites, which are specialized extensions of neurons that transmit and receive nerve impulses throughout the nervous system.
References
  1. Miyake N. et al, 2010, Am J Med Genet A. 152 (1): 215-7.
  2. Miyake N. et al., 2011, Invest Ophthalmol Vis Sci. 52 (9): 6321-8.
  3. Volk AE. et al., 2010, Graefes Arch Clin Exp Ophthalmol. 248 (9): 1351-7.

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