Mouse IL-18Rα ELISA Kit sinobiological KIT50094
$714.00
In stock
SKU
KIT50094
| Catalog No. | Size | Price (USD) |
| KIT50094-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Mouse IL-18Rα ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Mouse IL18R1. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Lysate |
| Sensitivity | 3.35 pg/mL |
| Assay range | 18.75-1200 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Mouse IL-18Rα ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse IL-18Rα protein in Lysate . It contains recombinant Mouse IL-18Rα, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations a series of mouse IL18 in a mid-range recombinant mouse IL18R1 control were assayed for interference. Interference was observed at concentrations 6 ng/mL. |
Synonyms: Il18r1 ELISA Kit, Mouse; Il18ralpha ELISA Kit, Mouse; Il1rrp ELISA Kit, Mouse
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Mouse IL18R1 ELISA Kit Standard Curve 125 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Mouse IL18R1 ELISA Kit Specificity 178 |
| Image 2 URL | Source image |
Background Information
| Full Name | interleukin 18 receptor 1 |
| Description | Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expressed in the lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from the brain, skeletal muscle, pancreas, and kidney. A high level of expression is found in Hodgkin disease cell lines. This receptor is specifically bound to interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IL18R1 contains 3 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. It is a single-pass type I membrane protein. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause. |
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