Rat IL1R1 ELISA Kit sinobiological KIT80028
$714.00
In stock
SKU
KIT80028
| Catalog No. | Size | Price (USD) |
| KIT80028-1 | 1 KIT (96 Tests) | $740.55 |
General Information
| Product name | Rat IL1R1 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Rat IL1R1. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 14.76 pg/mL |
| Assay range | 54.69-3500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Rat IL1R1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL1R1 protein in Serum . It contains recombinant Rat IL1R1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of rat IL1B and IL1RN at 35 ng/mL in a mid-range recombinant rat IL1R1 control were assayed for interference. No significant interference was observed. |
Synonyms: IL-1R-1 ELISA Kit, Rat; IL-1R-alpha ELISA Kit, Rat; IL-1RT-1 ELISA Kit, Rat; IL-1RT1 ELISA Kit, Rat; Il1r1 ELISA Kit, Rat; Il1ra ELISA Kit, Rat
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Rat IL1R1/IL-1R1/IL-1 RI ELISA Kit Standard Curve 28 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Rat IL1R1/IL-1R1/IL-1 RI ELISA Kit Specificity 166 |
| Image 2 URL | Source image |
Background Information
| Full Name | interleukin 1 receptor, type I |
| Description | Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA). IL-1R1/CD121a is an important mediator involved in many cytokines induced immune and inflammatory responses. This protein has been characterized by pharmacological and molecular techniques in the mouse brain. The spindle-shaped astrocytes enclose the wound, separating the healthy from damaged neural tissue. The shape change and subsequent repair processes are IL-1β activity-dependent, acting through the IL-1 type 1 receptor (IL-1R1), as co-application of the IL-1type 1 receptor antagonist protein (IL-1ra) blocks IL-1β induced effects. In the spleen, a slight increase in IL-1R ACP and IL-1R1 was observed during the first hours following LPS stimulation. In conclusion, IL-1R AcP mRNA is expressed in the brain and in other tissues where IL-1R1/CD121a transcripts are found. However, the regulation of its expression is distinct from IL-1R1/CD121a. The high level of expression and the lack of regulation of IL-1R AcP transcripts in the brain under inflammatory conditions suggest that the protein might be constitutively expressed in excess. |
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