Rat IL1R2 ELISA Kit sinobiological KIT80196
$714.00
In stock
SKU
KIT80196
| Catalog No. | Size | Price (USD) |
| KIT80196-1 | 1 Kit (96 Tests) | $740.55 |
| Catalog No. | Size | Price (USD) |
| KIT80196-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Rat IL1R2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Rat IL1R2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 4.7 pg/mL |
| Assay range | 15.63-1000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Rat IL1R2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL1R2 protein in Serum . It contains recombinant Rat IL1R2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of rat IL1B and rat IL1LB at 50 ng/mL in a mid-range recombinant rat IL1R2 control were assayed for interference. No significant interference was observed. |
Synonyms: Il-1r2 ELISA Kit, Rat; Il1r2 ELISA Kit, Rat; Il1rb ELISA Kit, Rat
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Rat IL-1R2/CD121b ELISA Kit Standard Curve 143 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Rat IL-1R2/CD121b ELISA Kit Specificity 165 |
| Image 2 URL | Source image |
Background Information
| Full Name | interleukin 1 receptor, type II |
| Description | Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. The pleiotropic cytokine IL1 is produced to regulate the development and maintenance of the inflammatory responses and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors that can bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2/CD121b has no signaling property and acts as a decoy for IL-1. IL-1R2/CD121b structurally consisting of a ligand-binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. |
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