Human IL-22 ELISA Kit sinobiological KIT13059
$400.00
In stock
SKU
KIT13059
| Catalog No. | Size | Price (USD) |
| KIT13059-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human IL-22 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural human IL22. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum,Urine,Plasma |
| Sensitivity | 2.8 pg/mL |
| Assay range | 4.69-300 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human IL-22 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-22 protein in Serum,Urine,Plasma . It contains recombinant Human IL-22, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the factors listed below at 50 ng/mL in a mid-range recombinant human IL22 control were assayed for interference. No significant interference was observed. |
Synonyms: IL-21 ELISA Kit, Human; IL-22 ELISA Kit, Human; IL-D110 ELISA Kit, Human; IL-TIF ELISA Kit, Human; ILTIF ELISA Kit, Human; MGC79382 ELISA Kit, Human; MGC79384 ELISA Kit, Human; TIFa ELISA Kit, Human; TIFIL-23 ELISA Kit, Human; UNQ3099/PRO10096 ELISA Kit, Human; zcyto18 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human IL22 ELISA Kit Standard Curve 23284 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human IL22 ELISA Kit Specificity 23285 |
| Image 2 URL | Source image |
Background Information
| Full Name | interleukin 22 |
| Description | IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 in cell signaling with other members of this family, IL-1, IL-26, IL-28A/B, and IL-29. IL22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL22 along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems. IL22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-1R2 receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (SIL-22R1). IL22 and IL-1 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. IL22 can contribute to immune disease through the stimulation of inflammatory responses, S1s, and defensins. IL22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-1. In some contexts, the pro-inflammatory versus tissue-protective functions of IL22 are regulated by the often co-expressed cytokine IL-17A. |
| References |
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