Human IL-4R ELISA Kit sinobiological KIT10402

$714.00
In stock
SKU
KIT10402
Catalog No.SizePrice (USD)
KIT10402-11 Kit (96 Tests)$740.55

General Information

Product nameHuman IL-4R ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human IL4R.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum,Cell supernatant
Sensitivity2.6 pg/mL
Assay range3.125-200 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human IL-4R ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-4R protein in Serum,Cell supernatant . It contains recombinant Human IL-4R, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of human IL4 at 2 ng/mL in a mid-range recombinant human IL4R control were assayed for interference. No significant interference was observed.

Synonyms: 582J2.1 ELISA Kit, Human; CD124 ELISA Kit, Human; IL-4RA ELISA Kit, Human; IL4RA ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman IL-4R/CD124 ELISA Kit Standard Curve 63
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman IL-4R/CD124 ELISA Kit Specificity 212
Image 2 URLSource image

Background Information

Full Nameinterleukin 4 receptor
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
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References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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