| Catalog No. | Size | Price (USD) |
| 50136-R076-50 | 50 µL | $177.58 |
| 50136-R076-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-IL-6 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse IL-6 |
| Immunogen | Recombinant Mouse IL-6 Protein (Catalog#50136-MNAE) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-6 (rM IL-6; Catalog#50136-MNAE; P08505; Phe25-Thr211). |
| Source | Monoclonal Rabbit IgG Clone #076 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Il-6 Antibody; Anti-Il6 Antibody
Background Information
| Full Name | interleukin 6 |
| Description | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
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| References |
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title: Ventromedial hypothalamus IL-6 signaling mediates the excessive aggressive behavior induced by late-gestational sleep deprivation in male mice.
authors: Fei Zhou; Xi Yu; ...; Haishui Shi
journal: Behavioral and brain functions : BBF
date: 2026-05-12
pmid: 42121275
cited_by_count: 0
techniques: Reflux
bioz_score: 94
