| Catalog No. | Size | Price (USD) |
| KIT11792-1 | 1 Kit (96 Tests) | $414.71 |
| KIT11792-5 | 5 Kit (96 Tests) | $1,747.71 |
| KIT11792-48 | 48 Tests | $266.60 |
General Information
| Product name | Human M-CSF/CSF1 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human MCSF. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum,Cell supernatant,Urine |
| Sensitivity | 4.57 pg/mL |
| Assay range | 14.06-900 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human M-CSF/CSF1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human M-CSF/CSF1 protein in Serum,Cell supernatant,Urine . It contains recombinant Human M-CSF/CSF1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the factors listed below at 50 ng/mL in a mid-range recombinant human MCSF control were assayed for interference. No significant interference was observed. |
Synonyms: CSF-1 ELISA Kit, Human; M-CSF ELISA Kit, Human; MCSF ELISA Kit, Human; MGC31930 ELISA Kit, Human; PG-M-CSF ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human M-CSF/CSF-1 ELISA Kit Standard Curve 17910 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human M-CSF/CSF-1 ELISA Kit Specificity 17924 |
| Image 2 URL | Source image |
Background Information
| Full Name | colony stimulating factor 1 (macrophage) |
| Description | Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression. |
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