Human Neuropilin-2/NRP2 ELISA Kit sinobiological KIT10695
$714.00
In stock
SKU
KIT10695
| Catalog No. | Size | Price (USD) |
| KIT10695-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human Neuropilin-2/NRP2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human NRP2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 42.98 pg/mL |
| Assay range | 125-8000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human Neuropilin-2/NRP2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Neuropilin-2/NRP2 protein in Serum . It contains recombinant Human Neuropilin-2/NRP2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: NP2 ELISA Kit, Human; NPN2 ELISA Kit, Human; PRO2714 ELISA Kit, Human; VEGF165R2 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human NRP2/Neuropilin-2 ELISA Kit Standard Curve 69 |
| Image 1 URL | Source image |
Background Information
| Full Name | neuropilin 2 |
| Description | Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellular signaling pathways via interacting with other cell surface receptors such as VEGF receptors and plexins. NRP-2 is well known for its role in facilitating axonal guidance during the development of the neuronal system, and additionally, it is also expressed in vascular endothelial cells and lymphatic endothelium where it affects proliferation, migration, angiogenesis, as well as the formation of small lymphatic vessels and capillaries. A recent study has identified NRP-2 as a polysialylation protein expressed in human dendritic cells and modulates DC-T Cell Interactions. Nearly all tumor cells express neuropilins and NRP-2 is predominantly expressed in neuronal tumors and melanomas. Furthermore, it is suggested that as the specific ligand for NRP-2, SEMA 3F inhibits tumor angiogenesis, and metastasis. |
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