Human Beta-NGF ELISA Kit sinobiological KIT11050

$400.00
In stock
SKU
KIT11050
Catalog No.SizePrice (USD)
KIT11050-11 Kit (96 Tests)$414.71
KIT11050-55 Kit (96 Tests)$1,747.71
KIT11050-4848 Tests$266.60

General Information

Product nameHuman Beta-NGF ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human β-NGF.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeCell supernatant
Sensitivity0.77 pg/mL
Assay range4.69-300 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human Beta-NGF ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Beta-NGF protein in Cell supernatant . It contains recombinant Human Beta-NGF, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of the factors listed below at 50 ng/mL in a mid-range recombinant human β-NGF control were assayed for interference. No significant interference was observed. High significant interference were observed within standard curve of recombinant mouse β-NGF.

Synonyms: Beta-NGF ELISA Kit, Human; HSAN5 ELISA Kit, Human; NGFB ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman NGF ELISA Kit Standard Curve 25348
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman NGF ELISA Kit Specificity 25349
Image 2 URLSource image

Background Information

Full Namenerve growth factor (beta polypeptide)
DescriptionNerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Related Pathways
  • Death Receptor Signaling
References
  1. Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
  2. Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
  3. Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.

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