Human PD-1 ELISA Kit sinobiological KIT10377
$714.00
In stock
SKU
KIT10377
| Catalog No. | Size | Price (USD) |
| KIT10377-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human PD-1 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human PD1. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 1.27 pg/mL |
| Assay range | 3.91-250 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human PD-1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human PD-1 protein in Serum . It contains recombinant Human PD-1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the factors listed below at 10 ng/mL in a mid-range recombinant human PD1 control were assayed for interference. No significant interference was observed. |
Synonyms: CD279 ELISA Kit, Human; hPD-1 ELISA Kit, Human; hPD-l ELISA Kit, Human; hSLE1 ELISA Kit, Human; PD-1 ELISA Kit, Human; PD1 ELISA Kit, Human; SLEB2 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human PD-1 ELISA Kit Standard Curve 23912 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human PD-1 ELISA Kit Specificity 23913 |
| Image 2 URL | Source image |
Background Information
| Full Name | programmed cell death 1 |
| Description | Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. Furthermore, PD1 is shown to be a regulator of virus-specific CD8+ T cell survival in HIV infection. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function. |
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