Mouse PLA2G1B ELISA Kit sinobiological KIT50329

$714.00
In stock
SKU
KIT50329
Catalog No.SizePrice (USD)
KIT50329-11 KIT (96 Tests)$740.55

General Information

Product nameMouse PLA2G1B ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Mouse PLA2G1B.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity0.14 pg/mL
Assay range2.82-180 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Mouse PLA2G1B ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse PLA2G1B protein in Serum . It contains recombinant Mouse PLA2G1B, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: Pla2 ELISA Kit, Mouse; Pla2a ELISA Kit, Mouse; Pla2g1b ELISA Kit, Mouse; sPLA2IB ELISA Kit, Mouse

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextMouse PLA2G1B ELISA Kit Standard Curve 25
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextMouse PLA2G1B ELISA Kit Specificity 172
Image 2 URLSource image

Background Information

Full Namephospholipase A2, group IB (pancreas)
Descriptionphospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic Phospholipase A2 / PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of Phospholipase A2 / PLA2G1B have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets. Mice lacking in Phospholipase A2 / PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
References
  1. Labonté,E.D. et al., 2006, Diabetes. 55 (4) :935-41.
  2. Mounier,C.M. et al.,2008, Br J Cancer. 98 (3):587-95.
  3. Hui,D.Y. et al., 2009, Br J Pharmacol. 157 (7):1263-9.
  4. Labonté,E.D. et al., 2010, FASEB J. 24 (7):2516-24.

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