Human RAGE ELISA Kit sinobiological KIT11629
$400.00
In stock
SKU
KIT11629
| Catalog No. | Size | Price (USD) |
| KIT11629-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human RAGE ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human RAGE. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum,Plasma |
| Sensitivity | 0.28 pg/mL |
| Assay range | 15.625-1000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human RAGE ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human RAGE protein in Serum,Plasma . It contains recombinant Human RAGE, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: RAGE ELISA Kit, Human; SCARJ1 ELISA Kit, Human; sRAGE ELISA Kit, Human
Background Information
| Full Name | advanced glycosylation end product-specific receptor |
| Description | Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, and inflammatory responses. However, RAGE also has roles in the pathogenesis of renal disorders that are not associated with diabetes, such as obesity-related glomerulopathy, doxorubicin-induced nephropathy, hypertensive nephropathy, lupus nephritis, renal amyloidosis, and ischemic renal injuries. RAGE represents an important factor in innate immunity against pathogens, but it also interacts with endogenous ligands, resulting in chronic inflammation. RAGE signaling has been implicated in multiple human illnesses, including atherosclerosis, arthritis, Alzheimer's disease, atherosclerosis and aging associated diseases. |
| References |
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