Mouse Alpha 2 Antiplasmin/SerpinF2 ELISA Kit sinobiological KIT50167
$714.00
In stock
SKU
KIT50167
| Catalog No. | Size | Price (USD) |
| KIT50167-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Mouse Alpha 2 Antiplasmin/SerpinF2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Mouse SERPINF2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 0.46 pg/mL |
| Assay range | 15.63-1000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Mouse Alpha 2 Antiplasmin/SerpinF2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse Alpha 2 Antiplasmin/SerpinF2 protein in Serum . It contains recombinant Mouse Alpha 2 Antiplasmin/SerpinF2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: Pli ELISA Kit, Mouse; Serpimf2 ELISA Kit, Mouse; Serpinf2 ELISA Kit, Mouse
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Mouse SerpinF2 ELISA Kit Standard Curve 129 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Mouse SerpinF2 ELISA Kit Specificity 170 |
| Image 2 URL | Source image |
Background Information
| Full Name | serpin peptidase inhibitor, clade F, member 2 |
| Description | SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of trypsin and chymotrypsin. This protease is produced mainly by liver and kidney, and also expressed in muscle, intestine, central nervous system, and placenta at a moderate level. It is indicated that Serpin F2 is a key regulator of plasmin-mediated proteolysis in these tissues. Alpha-2 AP is an unusual serpin in that it contains extensive N- and C-terminal sequences flanking the serpin domain. The N-terminal sequence is crosslinked to fibrin by factor XIIIa, whereas the C-terminal region mediates the initial interaction with plasmin. SerpinF2 is one of the inhibitors of fibrinolysis, which acts as the primary inhibitor of plasmin(ogen). It is a specific plasmin inhibitor, and is important in modulating the effectiveness and persistence of fibrin with respect to its susceptibility to digestion and removal by plasmin. Alpha-2 AP plays the dominant role in inhibiting both plasma clot lysis and thrombus lysis, and accordingly, the congenital deficiency of Alpha-2 antiplasmin causes a rare bleeding disorder because of increased fibrinolysis. Thus, it may be a useful target for developing more effective treatment of thrombotic diseases. |
| References |
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