Human SLAMF6 ELISA Kit sinobiological KIT11945

$714.00
In stock
SKU
KIT11945
Catalog No.SizePrice (USD)
KIT11945-11 Kit (96 Tests)$740.55

General Information

Product nameHuman SLAMF6 ELISA Kit
SpecificityThis assay recognizes recombinant human SLAMF6.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeRecombinant protein
Sensitivity13.01 pg/mL
Assay range15.63-1000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human SLAMF6 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human SLAMF6 protein in Recombinant protein . It contains recombinant Human SLAMF6, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: CD352 ELISA Kit, Human; KALI ELISA Kit, Human; KALIb ELISA Kit, Human; Ly108 ELISA Kit, Human; NTB-A ELISA Kit, Human; NTBA ELISA Kit, Human; SF2000 ELISA Kit, Human; UNQ6123/PRO20080 ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman Ly108/SLAMF6 ELISA Kit Standard Curve 110
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman Ly108/SLAMF6 ELISA Kit Specificity 151
Image 2 URLSource image

Background Information

Full NameSLAM family member 6
DescriptionSLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Research Areas
  • ITIM/ITAM Immunoreceptors and Related Molecules
References
  1. Gray CW. et al., 2000, Eur J Biochem. 267 (18): 5699-710.
  2. Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
  3. Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
  4. Claus M. et al., 2007, Front Biosci. 13: 956-65.

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