| Catalog No. | Size | Price (USD) |
| 14178-T56-50 | 50 µL | $147.96 |
| 14178-T56-100 | 100 µL | $251.64 |
| 14178-T56-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-LSP1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human LSP1 |
| Immunogen | Recombinant Human LSP1 Protein (Catalog#14178-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human LSP1 (rh LSP1; Catalog#14178-H08H; AAH01785.1; Met1-Pro339). LSP1 specific IgG was purified by Human LSP1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-pp52 Antibody; Anti-WP34 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human LSP1 in human tonsil with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human LSP1 Immunohistochemistry(IHC) 3924 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human LSP1 in human tonsil with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Human LSP1 Immunohistochemistry(IHC) 3925 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining of human LSP1 in human tonsil with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 3 Alt Text | Human LSP1 Western blot (WB) 6707 |
| Image 3 URL | Source image |
Background Information
| Full Name | lymphocyte-specific protein 1 |
| Description | LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. LSP1 is a lymphocyte-specific intracellular Ca2(+)-binding protein. LSP1 localizes to nascent phagocytic cups during Fcgamma receptor-mediated phagocytosis, where it displays the same spatial and temporal distribution as the actin cytoskeleton. Down-regulation of LSP1 severely reduces the phagocytic activity of macrophages, clearly demonstrating a crucial role for this protein in Fcgamma receptor-mediated phagocytosis. LSP1, expressed in endothelial cells, plays a pivotal role in regulating subsequent recruitment steps following leukocyte adhesion. |
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-HD09MA2327-WB.png){kind=link}