| Catalog No. | Size | Price (USD) |
| 103953-T08-50 | 50 µL | $147.96 |
| 103953-T08-100 | 100 µL | $251.64 |
| 103953-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-FRMPD2 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FRMPD2 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human FRMPD2 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human FRMPD2, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MGC35285 Antibody; Anti-PDZD5C Antibody; Anti-PDZK4 Antibody; Anti-PDZK5C Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human FRMPD2 in human kidney with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human FRMPD2 Immunohistochemistry(IHC) 19944 |
| Image 1 URL | Source image |
Background Information
| Description | Multi-PDZ (PSD-95/Discs large/Zonula-occludens-1) domain proteins play a crucial role in the establishment and maintenance of cell polarization. The multi-PDZ domain protein FRMPD2 is a scaffolding protein consisting of an N-terminal KIND domain, a FERM domain and three PDZ domains. The scaffold proteins Frmpd2 is localized at the basolateral membranes of polarized epithelial cells and associated with tight junction formation. Frmpd2 is specifically expressed at postsynaptic membrane. Frmpd2 is probably involved in synaptic NMDA receptors-mediated neural excitatory and neurotoxicity in a PDZ2 domain-dependent manner. |
| References |
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