Human ST2/IL-1 RL1 ELISA Kit sinobiological KIT10105

$400.00
In stock
SKU
KIT10105
Catalog No.SizePrice (USD)
KIT10105-11 Kit (96 Tests)$414.71

General Information

Product nameHuman ST2/IL-1 RL1 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human IL1R4.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity6.22 pg/mL
Assay range12.5-800 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human ST2/IL-1 RL1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human ST2/IL-1 RL1 protein in Serum . It contains recombinant Human ST2/IL-1 RL1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: DER4 ELISA Kit, Human; FIT-1 ELISA Kit, Human; IL33R ELISA Kit, Human; ST2 ELISA Kit, Human; ST2L ELISA Kit, Human; ST2V ELISA Kit, Human; T1 ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman IL1RL1/IL‑1 R4 ELISA Kit Standard Curve 34
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman IL1RL1/IL‑1 R4 ELISA Kit Specificity 214
Image 2 URLSource image

Background Information

Full Nameinterleukin 1 receptor-like 1
DescriptionIL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
Related Pathways
  • IL1 signaling pathway
References
  1. Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
  2. Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.

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