Mouse TNFR-2 / CD120b ELISA Kit sinobiological KIT50128
$400.00
In stock
SKU
KIT50128
| Catalog No. | Size | Price (USD) |
| KIT50128-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Mouse TNFR-2 / CD120b ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural mouse TNFRSF1B. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 4.1 pg/mL |
| Assay range | 6.25-400 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Mouse TNFR-2 / CD120b ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TNFR-2 / CD120b protein in Serum . It contains recombinant Mouse TNFR-2 / CD120b, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: CD120b ELISA Kit, Mouse; p75 ELISA Kit, Mouse; TNF-alphaR2 ELISA Kit, Mouse; TNF-R-II ELISA Kit, Mouse; TNF-R2 ELISA Kit, Mouse; TNF-R75 ELISA Kit, Mouse; TNFalpha-R2 ELISA Kit, Mouse; TNFBR ELISA Kit, Mouse; Tnfr-1 ELISA Kit, Mouse; Tnfr-2 ELISA Kit, Mouse; Tnfr2 ELISA Kit, Mouse; TNFR80 ELISA Kit, Mouse; TNFRII ELISA Kit, Mouse; Tnfrsf1b ELISA Kit, Mouse
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Mouse TNFR2/TNFRSF1B/CD120b ELISA Kit Standard Curve 126 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Mouse TNFR2/TNFRSF1B/CD120b ELISA Kit Specificity 167 |
| Image 2 URL | Source image |
Background Information
| Full Name | tumor necrosis factor receptor superfamily, member 1b |
| Description | Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2/CD120b/TNFRSF1B is not a major contributing factor to the genetic risk of type 2 diabetes, its associated peripheral neuropathy and hypertension and related metabolic traits in North Indians. Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B) has been reported to be associated with SLE risk in Japanese populations. TNFR2/CD120b/TNFRSF1B serves as a receptor with high affinity for TNFSF2 and approximately 5-fold lower affinity for homotrimeric TNFSF1. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. |
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