| Catalog No. | Size | Price (USD) |
| 12885-T52-50 | 50 µL | $147.96 |
| 12885-T52-100 | 100 µL | $251.64 |
| 12885-T52-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-MAX Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human MAX |
| Immunogen | Recombinant Human MYC associated factor X protein (Catalog#12885-H20B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human MYC associated factor X (rh MYC associated factor X; Catalog#12885-H20B; NP_002373; Met1-Ser160). MYC associated factor X specific IgG was purified by Human MYC associated factor X affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-bHLHd4 Antibody; Anti-bHLHd5 Antibody; Anti-bHLHd6 Antibody; Anti-bHLHd7 Antibody; Anti-bHLHd8 Antibody; Anti-PDMCS Antibody
Image / Experimental Information
| Image 1 Description | MAX was immunoprecipitated using: Lane A:0.5 mg Jurkat Whole Cell Lysate Lane B:0.5 mg Hela Whole Cell Lysate Lane C:0.5 mg 293T Whole Cell Lysate Lane D:0.5 mg A549 Whole Cell Lysate 2 µL anti-MAX rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-MAX rabbit polyclonal antibody,at 1:330 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 23 kDa Observed band size: 23 kDa |
| Image 1 Alt Text | Human MYC associated factor X Immunoprecipitation(IP) 6044 |
| Image 1 URL | Source image |
| Image 2 Description | MAX was immunoprecipitated using: Lane A:0.5 mg Jurkat Whole Cell Lysate Lane B:0.5 mg Hela Whole Cell Lysate Lane C:0.5 mg 293T Whole Cell Lysate Lane D:0.5 mg A549 Whole Cell Lysate 2 µL anti-MAX rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-MAX rabbit polyclonal antibody,at 1:330 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 23 kDa Observed band size: 23 kDa |
| Image 2 Alt Text | Human MYC associated factor X Western blot (WB) 6670 |
| Image 2 URL | Source image |
Background Information
| Full Name | MYC associated factor X |
| Description | MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1, and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation, and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. MYC associated factor X may also repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Multiple alternatively spliced transcript variants have been described for MYC associated factor X gene but the full-length nature for some of them is unknown. |
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