Mouse TNFR1/CD120a ELISA Kit sinobiological KIT50496

$400.00
In stock
SKU
KIT50496
Catalog No.SizePrice (USD)
KIT50496-11 KIT (96 Tests)$414.71

General Information

Product nameMouse TNFR1/CD120a ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Mouse TNFRSF1A.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity5.60 pg/mL
Assay range7.82-500 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Mouse TNFR1/CD120a ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TNFR1/CD120a protein in Serum . It contains recombinant Mouse TNFR1/CD120a, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of mouse TNFa(80-235) at 5 ng/mL in a mid-range recombinant mouse TNFRSF1A control were assayed for interference. No significant interference was observed.

Synonyms: CD120a ELISA Kit, Mouse; FPF ELISA Kit, Mouse; p55 ELISA Kit, Mouse; p55-R ELISA Kit, Mouse; TNF-alphaR1 ELISA Kit, Mouse; TNF-R ELISA Kit, Mouse; TNF-R-I ELISA Kit, Mouse; TNF-R1 ELISA Kit, Mouse; TNF-R55 ELISA Kit, Mouse; TNFalpha-R1 ELISA Kit, Mouse; TNFAR ELISA Kit, Mouse; Tnfr-1 ELISA Kit, Mouse; Tnfr-2 ELISA Kit, Mouse; Tnfr1 ELISA Kit, Mouse; TNFR60 ELISA Kit, Mouse; TNFRI ELISA Kit, Mouse; TNFRp55 ELISA Kit, Mouse; Tnfrsf1a ELISA Kit, Mouse

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextMouse TNFR1/TNFRSF1A/CD120a ELISA Kit Standard Curve 27
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextMouse TNFR1/TNFRSF1A/CD120a ELISA Kit Specificity 168
Image 2 URLSource image

Background Information

Full Nametumor necrosis factor receptor superfamily member 1A
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
Research Areas
  • Neuroinflammation
Related Pathways
  • Death Receptor Signaling
  • NF-kB (NFkB) Pathway
  • TNF Signaling
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  4. Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.

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