Human TROP-2 ELISA Kit sinobiological KIT10428
$714.00
In stock
SKU
KIT10428
| Catalog No. | Size | Price (USD) |
| KIT10428-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human TROP-2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human TROP2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 2.33 pg/mL |
| Assay range | 23.44-1500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human TROP-2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human TROP-2 protein in Serum . It contains recombinant Human TROP-2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: EGP-1 ELISA Kit, Human; EGP1 ELISA Kit, Human; GA733-1 ELISA Kit, Human; GA7331 ELISA Kit, Human; GP50 ELISA Kit, Human; M1S1 ELISA Kit, Human; TROP2 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human TROP-2/TACSTD2/TACD2 ELISA Kit Standard Curve 17908 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human TROP-2/TACSTD2/TACD2 ELISA Kit Specificity 17922 |
| Image 2 URL | Source image |
Background Information
| Full Name | tumor-associated calcium signal transducer 2 |
| Description | TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate. |
| Research Areas |
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| References |
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title: Cellular landscape and diagnostic value of TROP2 in cerebrospinal fluid of lung adenocarcinoma leptomeningeal metastases
authors: Zhe Wang; Jie Luo; ...; Haoyu Ruan
journal: NPJ precision oncology
date: 2026-03-24
pmid: 41876785
cited_by_count: 0
techniques: Biomarker Discovery; Control; Diagnostic Assay; Enzyme-linked Immunosorbent Assay; Software
bioz_score: 94
title: Energy Decomposition-Driven Design of Trop2-Targeting Peptide.
authors: Yu-Chao Meng; He Liu; ...; Qin Ouyang
journal: Cell biochemistry and biophysics
date: 2025-12-01
pmid: 40779128
doi: 10.1007/s12013-025-01866-4
cited_by_count: 0
techniques: CCK-8 Assay; Enzyme-linked Immunosorbent Assay; Sandwich ELISA
bioz_score: 93
title: Efficacy of anti-Trop-2-SN-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
authors: Serengulam V. Govindan; David M. Goldenberg
date: 2021-12-07
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay; Incubation; Recombinant
bioz_score: 94
title: Combination of ABCG2 inhibitors with sacituzumab govitecan (IMMU-132) overcomes resistance to SN-38 in Trop-2 expressing cancers
authors: Chien-Hsing Chang; David M. Goldenberg
date: 2021-03-23
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay; Incubation; Recombinant
bioz_score: 94
title: Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
authors: Serengulam V. Govindan; David M. Goldenberg
date: 2021-02-16
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay; Incubation; Recombinant
bioz_score: 94
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