Human VEGFR3/FLT4 ELISA Kit sinobiological KIT10806

$400.00
In stock
SKU
KIT10806
Catalog No.SizePrice (USD)
KIT10806-11 Kit (96 Tests)$414.71

General Information

Product nameHuman VEGFR3/FLT4 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human VEGFR3.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity35 pg/mL
Assay range46.88-3000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human VEGFR3/FLT4 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human VEGFR3/FLT4 protein in Serum . It contains recombinant Human VEGFR3/FLT4, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferenceRecombinant human VEGFC does not cross-react in this assay but does interfere at concentrations greater than 0.5 ng/mL.

Synonyms: CHTD7 ELISA Kit, Human; FLT-4 ELISA Kit, Human; FLT41 ELISA Kit, Human; LMPH1A ELISA Kit, Human; LMPHM1 ELISA Kit, Human; PCL ELISA Kit, Human; VEGFR-3 ELISA Kit, Human; VEGFR3 ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman VEGFR3/FLT-4 ELISA Kit Standard Curve 74
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman VEGFR3/FLT-4 ELISA Kit Specificity 189
Image 2 URLSource image

Background Information

Full Namefms related tyrosine kinase 4
DescriptionVascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.
Research Areas
  • Cancer Drug Targets
  • Receptor Tyrosine Kinases (RTKs)
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Shushanov S, et al. (2000)VEGFc and VEGFR3 expression in human thyroid pathologies. Int J Cancer.86(1): 47-52.
  2. Iljin K, et al. (2001) VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J. 15(6): 1028-36.
  3. Liu XE, et al. (2004) Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 10(3): 352-5.
  4. Stearns ME, et al. (2004) Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Lab Invest. 84(6): 785-95.

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