| Catalog No. | Size | Price (USD) |
| T09B-54N-20 | 20 µg | $293.26 |
| T09B-54N-100 | 100 µg | $1,033.81 |
| T09B-54N-1000 | 1000 µg | $5,136.48 |
General Information
| Formulation | Supplied as sterile 50 mM Tris-HCl pH 7.5, 50-300 mM NaCl, 1 mM DTT, 10-25% glycerol Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Shipping | Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. |
| Stability & Storage | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Purity | For specific information on a given lot, see related technical data sheet. |
| Activity | For specific information on a given lot, see related technical data sheet. |
| Protein Construction | Recombinant full length Drosophila melanogaster tag-free Tau-361 was expressed in E. coli cells. |
| Expressed Host | E. coli |
| Species | Drosophila melanogaster |
| Molecule Mass | Observed MW ~53 kDa. Calculated MW ~41 kDa. |
| Technical Data Sheet by Lot # | X3468-8 |
Background Information
| Full Name | microtubule-associated protein tau |
| Description | MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs. |
| Related Pathways |
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| References |
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MDSD
