Anti-PD1 (Research Grade Nofazinlimab Biosimilar) sinobiological 68279-H001A

$714.00
In stock
SKU
68279-H001A
Catalog No.SizePrice (USD)
68279-H001A-55 mg$740.55
68279-H001A-2525 mg$2,221.66
68279-H001A-500500 µg$222.17

General Information

Product nameAnti-PD1 (Research Grade Nofazinlimab Biosimilar)
Species reactivityReacts with: Human
SpecificityPD1
PreparationThis product is a recombinant monoclonal antibody expressed from CHO cells.
SourceIgG4, Kappa
PurificationProtein A
FormulationHistidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0
ConjugateUnconjugated
Endotoxin≦ 1 EU/mg
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageAntibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Image / Experimental Information

Image 1 Description≥95 % as determined by SEC-HPLC.
Image 1 Alt TextHuman PD1-Nofazinlimab Enzyme linked immunosorbent assay (ELISA) 46229
Image 1 URLSource image

title: Syrosingopine enhances immune checkpoint blockade efficacy by inhibition of MCTs and metabolic reprogramming in triple-negative breast cancer.
authors: Liu Yang; Cunyu Tang; ...; Chao Wu
journal: Biochimica et biophysica acta. Molecular basis of disease
date: 2026-07-08
pmid: 42202910
doi: 10.1016/j.bbadis.2026.168308
cited_by_count: 0
techniques: Blocking Assay; Control; Expressing; Incubation; Stable Transfection
bioz_score: 95

title: Bifunctional protein against PD-1 and TGF-β
authors: Wei Zhao; Yingchun Li; ...; Tiantian Li
date: 2026-06-30
cited_by_count: 0
techniques: Control; Negative Control
bioz_score: 95

title: Formulation comprising anti-PD-1/HER2 bispecific antibody, method for preparing same and use thereof
authors: Yanghan Liu; Yidong Ma; ...; Kaisong Zhou
date: 2026-05-19
cited_by_count: 0
techniques: Activity Assay; Binding Assay; Blocking Assay; Direct ELISA; Incubation; Negative Control; Recombinant; Serial Dilution
bioz_score: 95

title: Anti-PD-1 antibody, antigen-binding fragment thereof and pharmaceutical use thereof
authors: Xiaoling Gu; Xin Ye; ...; Weikang Tao
date: 2025-09-30
cited_by_count: 0
techniques: Binding Assay; Concentration Assay; Enzyme-linked Immunosorbent Assay; In Vitro; Incubation
bioz_score: 95

title: PD-L1 + neutrophils mediate immune regulation of CD8 + T cells in halo nevi
authors: Yixuan Zhang; Yingying Xu; ...; Lu Liu
journal: Frontiers in Immunology
date: 2025-08-20
pmid: 40909278
doi: 10.3389/fimmu.2025.1628913
cited_by_count: 1
techniques: Fluorescence; Imaging; Immunofluorescence; Incubation; Microscopy; Polymer; Staining
bioz_score: 95

title: A Bifunctional Anti-PD-1/TGF-β Fusion Antibody Restores Antitumour Immunity and Remodels the Tumour Microenvironment
authors: Lidi Nan; Yuting Qin; ...; Alain Couvineau
journal: International Journal of Molecular Sciences
date: 2025-08-05
pmid: 40806691
doi: 10.3390/ijms26157567
cited_by_count: 3
techniques: Competitive ELISA; Enzyme-linked Immunosorbent Assay
bioz_score: 95

title: Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
authors: Serengulam V. Govindan; David M. Goldenberg
date: 2025-07-22
cited_by_count: 0
techniques: Migration
bioz_score: 95

title: Humanized anti-human-PD-1 antibody and methods of using them for cancer treatment
authors: Nicolas Poirier; Caroline Mary; ...; Sabrina Pengam
date: 2025-06-17
cited_by_count: 0
techniques: Competitive Binding Assay; Concentration Assay; Recombinant; Variant Assay
bioz_score: 95

title: Vaccine composition and uses thereof
authors: Nicholas Ede; Ursula Wiedermann; ...; Christoph Zielinski
date: 2025-05-27
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay; Incubation; Recombinant
bioz_score: 95

title: Silibinin enhanced the efficacy of albendazole in treating the muscular phase of experimental trichinellosis
authors: Mennat-Elrahman A. Fahmy; Marwa Esmat; ...; Iman R. Abdel Shafi
journal: Tropical animal health and production
date: 2025-05-07
pmid: 40332448
doi: 10.1007/s11250-025-04429-0
cited_by_count: 0
techniques: Formalin-fixed Paraffin-Embedded; Histopathology; Immunohistochemistry; Staining
bioz_score: 95

title: Design of a fragment crystallizable-engineered tetravalent bispecific antibody targeting programmed cell death-1 and vascular endothelial growth factor with cooperative biological effects.
authors: Tingting Zhong; Lingzhi Zhang; ...; Baiyong Li
journal: iScience
date: 2025-03-21
pmid: 40034861
cited_by_count: 18
techniques: Incubation; Proliferation Assay
bioz_score: 95

title: Preclinical Characterization of Efficacy and Pharmacodynamic Properties of Finotonlimab, a Humanized Anti-PD-1 Monoclonal Antibody.
authors: Yunqi Yao; Xiaoning Yang; ...; Liangzhi Xie
journal: Pharmaceuticals (Basel, Switzerland)
date: 2025-03-12
pmid: 40143171
cited_by_count: 2
bioz_score: 95

title: Development of Novel Short Peptide Inhibitor Targeted to Immune Checkpoint PD-1 LBD
authors: Xingyan Zhu; Yuping Wei; ...; Qiuhong Niu
journal: International Journal of Peptide Research and Therapeutics
date: 2025-03-07
doi: 10.1007/s10989-025-10707-0
cited_by_count: 0
techniques: Cell Viability Assay; Recombinant
bioz_score: 95

title: Effects of FAP + cancer-associated fibroblasts on anti-PD-1 immunotherapy and CD4 + T cell polarization in gastric cancer
authors: Jing Wu; Peng-Fei Zhang; ...; Hong Jiang
journal: Cancer Drug Resistance
date: 2025-01-01
doi: 10.20517/cdr.2025.97
cited_by_count: 0
techniques: Control; Injection
bioz_score: 95

title: Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD.
authors: Dianze Chen; Song Li; ...; Wenzhi Tian
journal: Journal of Pharmaceutical and Biomedical Analysis
date: 2024-08-22
pmid: 39197208
doi: 10.1016/j.jpba.2024.116431
cited_by_count: 1
techniques: Expressing; Flow Cytometry; Recombinant
bioz_score: 95

title: Anti-PD-1 antibodies and compositions
authors: Gunther Galler; Monika Gad; ...; Mikkel Pedersen
date: 2024-07-09
cited_by_count: 0
techniques: Concentration Assay; Injection
bioz_score: 95

title: Protein-type nanoparticles, preparation methods, and application thereof
authors: Jun Wang; Zhiting Cao; ...; Youyong Yuan
date: 2024-04-16
cited_by_count: 0
techniques: Binding Assay; Enzyme-linked Immunosorbent Assay; Functional Assay; Recombinant; Software
bioz_score: 95

title: Characterization of a novel T cell-engaging bispecific antibody for elimination of L1CAM-positive tumors.
authors: Yuan Yuan; Junyan Li; ...; Jianwei Zhu
journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
date: 2024-04-10
pmid: 38603888
doi: 10.1016/j.biopha.2024.116565
cited_by_count: 6
techniques: Clinical Proteomics; Concentration Assay; Enzyme-linked Immunosorbent Assay; Expressing; Flow Cytometry; In Vitro; In Vivo; Incubation; Protein Concentration; Staining
bioz_score: 95

title: Anti-PD-1 antibodies
authors: Najmia Amirina; Hareesh Chamarthi; ...; Sri Sahitya Vadde
date: 2023-05-02
cited_by_count: 0
techniques: Activation Assay; Enzyme-linked Immunosorbent Assay; Inhibition; Recombinant
bioz_score: 95

title: Tuning Surface Plasmon Resonance Responses through Size and Crosslinking Control of Multivalent Protein Binding-Capable Nanoscale Hydrogels.
authors: Jie Ying Teoh; Suhwan Jeon; ...; Dongwon Yoo
journal: ACS Biomaterials Science Engineering
date: 2022-07-12
pmid: 35658391
doi: 10.1021/acsbiomaterials.2c00250
cited_by_count: 5
techniques: Purification; Recombinant; Saline
bioz_score: 95

title: Humanized anti-human-PD-1 antibody and its use in cancer treatment
authors: Nicolas Poirier; Caroline Mary; ...; Sabrina Pengam
date: 2022-06-07
cited_by_count: 0
techniques: Competitive Binding Assay; Concentration Assay; Recombinant; Variant Assay
bioz_score: 95

title: An automated, rapid fluorescent immunoassay to quantify serum soluble programmed death-1 (PD-1) protein using testing-on-a-probe biosensors.
authors: Jun Zhang; Lin Chen; ...; Yuxin Chen
journal: Clinical chemistry and laboratory medicine
date: 2022-05-25
pmid: 35535427
doi: 10.1515/cclm-2022-0166
cited_by_count: 2
techniques: Binding Assay; Biomarker Discovery; Bioprocessing; Recombinant
bioz_score: 95

title: Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition.
authors: Chang-Ling Gu; Hai-Xia Zhu; ...; Hao-Min Huang
journal: Acta pharmacologica Sinica
date: 2022-03-23
pmid: 33990766
doi: 10.1038/s41401-021-00683-8
cited_by_count: 32
techniques: Ex Vivo; Expressing; Labeling; Microscopy; Staining
bioz_score: 95

title: Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8 + T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma.
authors: Hailin Zhang; Yonghui Zhang; ...; Jiwu Wei
journal: Cellular oncology (Dordrecht)
date: 2022-03-08
pmid: 34491549
cited_by_count: 11
techniques: Concentration Assay; Enzyme-linked Immunosorbent Assay; Incubation
bioz_score: 95

title: Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement
authors: Zhidi Pan; Jie Chen; ...; Jianwei Zhu
journal: Acta Pharmaceutica Sinica. B
date: 2021-11-03
doi: 10.1016/j.apsb.2021.10.028
pmcid: 9279644
cited_by_count: 17
techniques: Expressing; FACS; Flow Cytometry; In Vitro; Incubation; Labeling; Lysis; Staining
bioz_score: 95

title: A PD-1 peptide antagonist exhibits potent anti-tumor and immune regulatory activity.
authors: Huimin Tao; Lu Cheng; ...; Zheng Qiu
journal: Cancer letters
date: 2021-03-25
pmid: 32805322
doi: 10.1016/j.canlet.2020.08.009
cited_by_count: 16
techniques: Activation Assay; Binding Assay; Cell Culture; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Labeling; Marker; Purification; Stable Transfection; Staining; Transfection
bioz_score: 95

title: Anti-PD-L1 DNA aptamer antagonizes the interaction of PD-1/PD-L1 with antitumor effect.
authors: Tian Gao; Zheng Mao; ...; Renjun Pei
journal: Journal of Materials Chemistry B
date: 2021-03-25
pmid: 33319876
doi: 10.1039/d0tb01668c
cited_by_count: 16
bioz_score: 95

title: Tumor-targeting anti-EGFR x anti-PD1 bispecific antibody inhibits EGFR-overexpressing tumor growth by combining EGFR blockade and immune activation with direct tumor cell killing
authors: Li Li; Lan Deng; ...; Haomin Huang
journal: Translational Oncology
date: 2020-10-22
pmid: 33129108
doi: 10.1016/j.tranon.2020.100916
pmcid: 7585148
cited_by_count: 30
techniques: ADCC Assay; Activation Assay; Binding Assay; Blocking Assay; Cell Based Assay; Control; Differential Scanning Calorimetry; Enzyme-linked Immunosorbent Assay; Immunofluorescence; In Vivo; Injection; Labeling; Marker; Microscopy; Molecular Weight; Negative Control; Positive Control; SDS Page; Staining; Transfection
bioz_score: 95

title: Isolation of DNA Aptamer Targeting PD-1 with an Antitumor Immunotherapy Effect.
authors: Tian Gao; Renjun Pei
journal: ACS Applied Bio Materials
date: 2020-09-21
pmid: 35019367
doi: 10.1021/acsabm.0c00919
cited_by_count: 19
techniques: Binding Assay; Fluorescence; Incubation; Microscopy; Modification; Oligonucleotide Assay; Recombinant; Sequencing
bioz_score: 95

title: Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor
authors: Yonghui Zhang; Junyi Wu; ...; Junhua Wu
journal: Frontiers In Bioengineering And Biotechnology
date: 2020-09-16
pmid: 33042975
pmcid: 7525182
cited_by_count: 25
techniques: Activation Assay; Amplification; Concentration Assay; Enzyme-linked Immunosorbent Assay; Enzyme-linked Immunospot; Expressing; Flow Cytometry; In Vivo; Incubation; Infection; Isolation; Labeling; Neutralization; Recombinant; Sequencing; Staining; Standard Deviation
bioz_score: 95

title: Recombinant Adenovirus Expressing a Soluble Fusion Protein PD-1/CD137L Subverts the Suppression of CD8 + T Cells in HCC
authors: Yonghui Zhang; Hailin Zhang; ...; Jiwu Wei
journal: Molecular Therapy
date: 2019-08-05
pmid: 31466933
doi: 10.1016/j.ymthe.2019.07.019
pmcid: 6838906
cited_by_count: 41
techniques: Centrifugation; Concentration Assay; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Imaging; Incubation; Recombinant; Western Blot
bioz_score: 95

title: Non-conventional inhibitory CD4 + Foxp3 − PD-1 hi T cells as a biomarker of immune checkpoint blockade activity
authors: Roberta Zappasodi; Sadna Budhu; ...; Jedd D. Wolchok
journal: Cancer cell
date: 2019-07-23
pmid: 29894689
doi: 10.1016/j.ccell.2018.05.009
pmcid: 6648657
cited_by_count: 92
techniques: Activation Assay; Avidin-Biotin Assay; Blocking Assay; Cell Culture; Co-Culture Assay; Derivative Assay; Expressing; Immunofluorescence; In Vitro; In Vivo; Incubation; Injection; Irradiation; Knock-Out; Labeling; Luminex; Multiplex Assay; Plasmid Preparation; Purification; Recombinant; Software; Staining; Suppression Assay; Transgenic Assay; Tumor Implantation
bioz_score: 95

title: Enhancement of Oncolytic Activity of oHSV Expressing IL-12 and Anti PD-1 Antibody by Concurrent Administration of Exosomes Carrying CTLA-4 miRNA
authors: Runbin Yan; Xusha Zhou; ...; Grace G Zhou
journal: Immunotherapy: Open Access
date: 2019-01-01
doi: 10.35248/2471-9552.19.5.154
cited_by_count: 0
techniques: Binding Assay; Enzyme-linked Immunosorbent Assay; Incubation; Purification
bioz_score: 95

title: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
authors: Carmela Passaro; Quazim Alayo; ...; Hiroshi Nakashima
journal: Clinical Cancer Research
date: 2018-10-02
doi: 10.1158/1078-0432.ccr-18-2311
cited_by_count: 82
techniques: Affinity Purification; Binding Assay; Centrifugation; Chromatography; Enzyme-linked Immunosorbent Assay; Expressing; Incubation; Lysis; Negative Control; Polyacrylamide Gel Electrophoresis; Protease Inhibitor; Purification; Recombinant; Sonication; Staining; Transfection; Western Blot
bioz_score: 95

title: Safety, anti-tumour activity, and pharmacokinetics of fixed-dose SHR-1210, an anti-PD-1 antibody in advanced solid tumours: a dose-escalation, phase 1 study
authors: Hongnan Mo; Jing Huang; ...; Binghe Xu
journal: British Journal of Cancer
date: 2018-05-14
pmid: 29755117
doi: 10.1038/s41416-018-0100-3
pmcid: 6162236
cited_by_count: 102
techniques: Binding Assay; Control; Enzyme-linked Immunosorbent Assay; In Vivo; Incubation; Produced
bioz_score: 95

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