Anti-PD1 (Research Grade Nofazinlimab Biosimilar) sinobiological 68279-H001A
| Catalog No. | Size | Price (USD) |
| 68279-H001A-5 | 5 mg | $740.55 |
| 68279-H001A-25 | 25 mg | $2,221.66 |
| 68279-H001A-500 | 500 µg | $222.17 |
| Catalog No. | Size | Price (USD) |
| 68279-H001A-5 | 5 mg | $740.55 |
| 68279-H001A-25 | 25 mg | $2,221.66 |
| 68279-H001A-500 | 500 µg | $222.17 |
General Information
| Product name | Anti-PD1 (Research Grade Nofazinlimab Biosimilar) |
| Species reactivity | Reacts with: Human |
| Specificity | PD1 |
| Preparation | This product is a recombinant monoclonal antibody expressed from CHO cells. |
| Source | IgG4, Kappa |
| Purification | Protein A |
| Formulation | Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0 |
| Conjugate | Unconjugated |
| Endotoxin | ≦ 1 EU/mg |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | ≥95 % as determined by SEC-HPLC. |
| Image 1 Alt Text | Human PD1-Nofazinlimab Enzyme linked immunosorbent assay (ELISA) 46229 |
| Image 1 URL | Source image |
title: Syrosingopine enhances immune checkpoint blockade efficacy by inhibition of MCTs and metabolic reprogramming in triple-negative breast cancer.
authors: Liu Yang; Cunyu Tang; ...; Chao Wu
journal: Biochimica et biophysica acta. Molecular basis of disease
date: 2026-07-08
pmid: 42202910
doi: 10.1016/j.bbadis.2026.168308
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techniques: Blocking Assay; Control; Expressing; Incubation; Stable Transfection
bioz_score: 95
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title: Formulation comprising anti-PD-1/HER2 bispecific antibody, method for preparing same and use thereof
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techniques: Activity Assay; Binding Assay; Blocking Assay; Direct ELISA; Incubation; Negative Control; Recombinant; Serial Dilution
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title: Anti-PD-1 antibody, antigen-binding fragment thereof and pharmaceutical use thereof
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date: 2025-09-30
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techniques: Binding Assay; Concentration Assay; Enzyme-linked Immunosorbent Assay; In Vitro; Incubation
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title: PD-L1 + neutrophils mediate immune regulation of CD8 + T cells in halo nevi
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journal: Frontiers in Immunology
date: 2025-08-20
pmid: 40909278
doi: 10.3389/fimmu.2025.1628913
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techniques: Fluorescence; Imaging; Immunofluorescence; Incubation; Microscopy; Polymer; Staining
bioz_score: 95
title: A Bifunctional Anti-PD-1/TGF-β Fusion Antibody Restores Antitumour Immunity and Remodels the Tumour Microenvironment
authors: Lidi Nan; Yuting Qin; ...; Alain Couvineau
journal: International Journal of Molecular Sciences
date: 2025-08-05
pmid: 40806691
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title: Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
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title: Humanized anti-human-PD-1 antibody and methods of using them for cancer treatment
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date: 2025-06-17
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techniques: Competitive Binding Assay; Concentration Assay; Recombinant; Variant Assay
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title: Vaccine composition and uses thereof
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techniques: Enzyme-linked Immunosorbent Assay; Incubation; Recombinant
bioz_score: 95
title: Silibinin enhanced the efficacy of albendazole in treating the muscular phase of experimental trichinellosis
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techniques: Formalin-fixed Paraffin-Embedded; Histopathology; Immunohistochemistry; Staining
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title: Design of a fragment crystallizable-engineered tetravalent bispecific antibody targeting programmed cell death-1 and vascular endothelial growth factor with cooperative biological effects.
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journal: iScience
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title: Preclinical Characterization of Efficacy and Pharmacodynamic Properties of Finotonlimab, a Humanized Anti-PD-1 Monoclonal Antibody.
authors: Yunqi Yao; Xiaoning Yang; ...; Liangzhi Xie
journal: Pharmaceuticals (Basel, Switzerland)
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bioz_score: 95
title: Development of Novel Short Peptide Inhibitor Targeted to Immune Checkpoint PD-1 LBD
authors: Xingyan Zhu; Yuping Wei; ...; Qiuhong Niu
journal: International Journal of Peptide Research and Therapeutics
date: 2025-03-07
doi: 10.1007/s10989-025-10707-0
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techniques: Cell Viability Assay; Recombinant
bioz_score: 95
title: Effects of FAP + cancer-associated fibroblasts on anti-PD-1 immunotherapy and CD4 + T cell polarization in gastric cancer
authors: Jing Wu; Peng-Fei Zhang; ...; Hong Jiang
journal: Cancer Drug Resistance
date: 2025-01-01
doi: 10.20517/cdr.2025.97
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techniques: Control; Injection
bioz_score: 95
title: Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD.
authors: Dianze Chen; Song Li; ...; Wenzhi Tian
journal: Journal of Pharmaceutical and Biomedical Analysis
date: 2024-08-22
pmid: 39197208
doi: 10.1016/j.jpba.2024.116431
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techniques: Expressing; Flow Cytometry; Recombinant
bioz_score: 95
title: Anti-PD-1 antibodies and compositions
authors: Gunther Galler; Monika Gad; ...; Mikkel Pedersen
date: 2024-07-09
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techniques: Concentration Assay; Injection
bioz_score: 95
title: Protein-type nanoparticles, preparation methods, and application thereof
authors: Jun Wang; Zhiting Cao; ...; Youyong Yuan
date: 2024-04-16
cited_by_count: 0
techniques: Binding Assay; Enzyme-linked Immunosorbent Assay; Functional Assay; Recombinant; Software
bioz_score: 95
title: Characterization of a novel T cell-engaging bispecific antibody for elimination of L1CAM-positive tumors.
authors: Yuan Yuan; Junyan Li; ...; Jianwei Zhu
journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
date: 2024-04-10
pmid: 38603888
doi: 10.1016/j.biopha.2024.116565
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techniques: Clinical Proteomics; Concentration Assay; Enzyme-linked Immunosorbent Assay; Expressing; Flow Cytometry; In Vitro; In Vivo; Incubation; Protein Concentration; Staining
bioz_score: 95
title: Anti-PD-1 antibodies
authors: Najmia Amirina; Hareesh Chamarthi; ...; Sri Sahitya Vadde
date: 2023-05-02
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techniques: Activation Assay; Enzyme-linked Immunosorbent Assay; Inhibition; Recombinant
bioz_score: 95
title: Tuning Surface Plasmon Resonance Responses through Size and Crosslinking Control of Multivalent Protein Binding-Capable Nanoscale Hydrogels.
authors: Jie Ying Teoh; Suhwan Jeon; ...; Dongwon Yoo
journal: ACS Biomaterials Science Engineering
date: 2022-07-12
pmid: 35658391
doi: 10.1021/acsbiomaterials.2c00250
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techniques: Purification; Recombinant; Saline
bioz_score: 95
title: Humanized anti-human-PD-1 antibody and its use in cancer treatment
authors: Nicolas Poirier; Caroline Mary; ...; Sabrina Pengam
date: 2022-06-07
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techniques: Competitive Binding Assay; Concentration Assay; Recombinant; Variant Assay
bioz_score: 95
title: An automated, rapid fluorescent immunoassay to quantify serum soluble programmed death-1 (PD-1) protein using testing-on-a-probe biosensors.
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date: 2022-05-25
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doi: 10.1515/cclm-2022-0166
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techniques: Binding Assay; Biomarker Discovery; Bioprocessing; Recombinant
bioz_score: 95
title: Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition.
authors: Chang-Ling Gu; Hai-Xia Zhu; ...; Hao-Min Huang
journal: Acta pharmacologica Sinica
date: 2022-03-23
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doi: 10.1038/s41401-021-00683-8
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techniques: Ex Vivo; Expressing; Labeling; Microscopy; Staining
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title: Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8 + T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma.
authors: Hailin Zhang; Yonghui Zhang; ...; Jiwu Wei
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date: 2022-03-08
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techniques: Concentration Assay; Enzyme-linked Immunosorbent Assay; Incubation
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date: 2021-11-03
doi: 10.1016/j.apsb.2021.10.028
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date: 2021-03-25
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techniques: Activation Assay; Binding Assay; Cell Culture; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Labeling; Marker; Purification; Stable Transfection; Staining; Transfection
bioz_score: 95
title: Anti-PD-L1 DNA aptamer antagonizes the interaction of PD-1/PD-L1 with antitumor effect.
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date: 2021-03-25
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title: Tumor-targeting anti-EGFR x anti-PD1 bispecific antibody inhibits EGFR-overexpressing tumor growth by combining EGFR blockade and immune activation with direct tumor cell killing
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journal: Translational Oncology
date: 2020-10-22
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doi: 10.1016/j.tranon.2020.100916
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cited_by_count: 30
techniques: ADCC Assay; Activation Assay; Binding Assay; Blocking Assay; Cell Based Assay; Control; Differential Scanning Calorimetry; Enzyme-linked Immunosorbent Assay; Immunofluorescence; In Vivo; Injection; Labeling; Marker; Microscopy; Molecular Weight; Negative Control; Positive Control; SDS Page; Staining; Transfection
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title: Isolation of DNA Aptamer Targeting PD-1 with an Antitumor Immunotherapy Effect.
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date: 2020-09-16
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techniques: Activation Assay; Amplification; Concentration Assay; Enzyme-linked Immunosorbent Assay; Enzyme-linked Immunospot; Expressing; Flow Cytometry; In Vivo; Incubation; Infection; Isolation; Labeling; Neutralization; Recombinant; Sequencing; Staining; Standard Deviation
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journal: Molecular Therapy
date: 2019-08-05
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cited_by_count: 41
techniques: Centrifugation; Concentration Assay; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Imaging; Incubation; Recombinant; Western Blot
bioz_score: 95
title: Non-conventional inhibitory CD4 + Foxp3 − PD-1 hi T cells as a biomarker of immune checkpoint blockade activity
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journal: Cancer cell
date: 2019-07-23
pmid: 29894689
doi: 10.1016/j.ccell.2018.05.009
pmcid: 6648657
cited_by_count: 92
techniques: Activation Assay; Avidin-Biotin Assay; Blocking Assay; Cell Culture; Co-Culture Assay; Derivative Assay; Expressing; Immunofluorescence; In Vitro; In Vivo; Incubation; Injection; Irradiation; Knock-Out; Labeling; Luminex; Multiplex Assay; Plasmid Preparation; Purification; Recombinant; Software; Staining; Suppression Assay; Transgenic Assay; Tumor Implantation
bioz_score: 95
title: Enhancement of Oncolytic Activity of oHSV Expressing IL-12 and Anti PD-1 Antibody by Concurrent Administration of Exosomes Carrying CTLA-4 miRNA
authors: Runbin Yan; Xusha Zhou; ...; Grace G Zhou
journal: Immunotherapy: Open Access
date: 2019-01-01
doi: 10.35248/2471-9552.19.5.154
cited_by_count: 0
techniques: Binding Assay; Enzyme-linked Immunosorbent Assay; Incubation; Purification
bioz_score: 95
title: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
authors: Carmela Passaro; Quazim Alayo; ...; Hiroshi Nakashima
journal: Clinical Cancer Research
date: 2018-10-02
doi: 10.1158/1078-0432.ccr-18-2311
cited_by_count: 82
techniques: Affinity Purification; Binding Assay; Centrifugation; Chromatography; Enzyme-linked Immunosorbent Assay; Expressing; Incubation; Lysis; Negative Control; Polyacrylamide Gel Electrophoresis; Protease Inhibitor; Purification; Recombinant; Sonication; Staining; Transfection; Western Blot
bioz_score: 95
title: Safety, anti-tumour activity, and pharmacokinetics of fixed-dose SHR-1210, an anti-PD-1 antibody in advanced solid tumours: a dose-escalation, phase 1 study
authors: Hongnan Mo; Jing Huang; ...; Binghe Xu
journal: British Journal of Cancer
date: 2018-05-14
pmid: 29755117
doi: 10.1038/s41416-018-0100-3
pmcid: 6162236
cited_by_count: 102
techniques: Binding Assay; Control; Enzyme-linked Immunosorbent Assay; In Vivo; Incubation; Produced
bioz_score: 95