| Catalog No. | Size | Price (USD) |
| 205693-T10-50 | 50 µL | $147.96 |
| 205693-T10-100 | 100 µL | $251.64 |
| 205693-T10-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CHD5 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CHD5 |
| Immunogen | E. coli-derived Human CHD5 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CHD5 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CHD-5 Antibody; Anti-KIAA0444 Antibody; Anti-PMNDS Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CHD5 in cynomolgus cerebellum with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CHD5 Immunohistochemistry(IHC) 25846 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CHD5 in cynomolgus cerebellum with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CHD5 Immunofluorescence(IF) 25847 |
| Image 2 URL | Source image |
Background Information
| Description | Chromodomain helicase DNA binding protein 5 (CHD5) is a member of CHD protein family which acts in chromatin organization, regulation of transcription and also genomic stability and cancer prevention. CHD5 functions by forming a nucleosome remodeling and deacetylation (NuRD) complex that regulates the transcription of particular genes. CHD5 is preferentially expressed in the nervous system and testis. CHD5 acts as a tumor suppressor n gliomas and a variety of other tumor types, including breast, colon, lung, ovary, and prostate cancers. CHD5 may serve as an independent prognostic biomarker for colorectal patients. |
| References |
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