| Catalog No. | Size | Price (USD) |
| 10202-RP01-20 | 20 µL | $88.87 |
| 10202-RP01-100 | 100 µL | $251.64 |
| 10202-RP01-200 | 200 µL | $370.28 |
General Information
| Product name | Human cytomegalovirus (HCMV) Glycoprotein B / gB Antibody, Rabbit PAb |
| Validated applications | ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | Human cytomegalovirus (HCMV) Glycoprotein B / gB |
| Immunogen | Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB protein (Catalog#10202-V08H1) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB (Catalog#10202-V08H1; AAA45920.1; Met1-Lys700 & Arg777-Val907). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Description | Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium. |
| References |
|
title: Oncolytic cytomegaloviruses expressing EGFR-retargeted fusogenic glycoprotein complex and drug-controllable interleukin 12
authors: Haifei Jiang; Rebecca Nace; ...; Stephen J. Russell
journal: Cell Reports Medicine
date: 2024-12-17
pmid: 39694038
pmcid: 11866437
cited_by_count: 2
techniques: Autoradiography; Enzyme-linked Immunosorbent Assay; Enzyme-linked Immunospot; Extraction; Liposomes; Lysis; Plasmid Preparation; Purification; Recombinant; Sequencing; Software; Staining; Virus; Western Blot
bioz_score: 94
title: Fine Mapping the Interaction Between Dendritic Cell-Specific Intercellular Adhesion Molecule (ICAM)-3-Grabbing Nonintegrin and the Cytomegalovirus Envelope Glycoprotein B
authors: Coraline Chéneau; Flora Coulon; ...; Franck Halary
journal: The Journal of Infectious Diseases
date: 2018-08-01
pmid: 29648611
doi: 10.1093/infdis/jiy194
pmcid: 6049025
cited_by_count: 11
techniques: Binding Assay; Clone Assay; Derivative Assay; Flow Cytometry; Fluorescence; Infection; Inhibition; Purification; Recombinant
bioz_score: 94
