| Catalog No. | Size | Price (USD) |
| 202707-T08-50 | 50 µL | $147.96 |
| 202707-T08-100 | 100 µL | $251.64 |
| 202707-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CR1/CD35 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CR1/CD35 |
| Immunogen | E. coli-derived Human CR1 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CR1 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-C3BR Antibody; Anti-C4BR Antibody; Anti-CD35 Antibody; Anti-KN Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CR1 in human tonsil with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CR1 Immunohistochemistry(IHC) 20817 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CR1 in human tonsil with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CR1 Immunohistochemistry(IHC) 20818 |
| Image 2 URL | Source image |
Background Information
| Full Name | complement component 3b/4b receptor 1 (Knops blood group) |
| Description | Complement receptor type 1 (CR1) is a multi-modular membrane receptor composed of 30 homologous complement control protein modules (CCP) organized in four different functional regions called long homologous repeats (LHR A, B, C, and D). CR1 is a receptor for complement-opsonins C3b and C4b and specifically interacts through pairs of CCP modules located in LHR A, B, and C. Human CR1 plays a role in the clearance of complement opsonized molecules and may facilitate the entry of pathogens into host cells. Lower CR1 expression has been associated with susceptibility to systemic lupus erythematosus (SLE). In contrast, subjects displaying lower CR1 expression are protected against severe manifestations of falciparum malaria. The CR1 gene was shown to be involved in Alzheimer's disease (AD). |
| References |
|
title: Synonymous codon usage regulates translation initiation
authors: Barrington Chloe L.; Koch Amanda L.; ...; Rissland Olivia S.
journal: bioRxiv
date: 2022-05-13
doi: 10.1101/2022.05.13.491887
cited_by_count: 2
techniques: Immunoprecipitation; Incubation; Lysis; Protease Inhibitor; Transferring; Western Blot
bioz_score: 91
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