Anti-CD32B/Fcgr2b Antibody (APC), Mouse Monoclonal sinobiological 90014-MM12-A

$157.00
In stock
SKU
90014-MM12-A
Catalog No.SizePrice (USD)
90014-MM12-A-2525 Tests$162.92
90014-MM12-A-100100 Tests$325.84

General Information

Product nameAnti-CD32B/Fcgr2b Antibody (APC), Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Cynomolgus
SpecificityCynomolgus CD32B/Fcgr2b
ImmunogenRecombinant Cynomolgus CD32b/FCGR2B/Fc gamma RIIB Protein (Catalog#90014-C08H)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Cynomolgus CD32b/FCGR2B/Fc gamma RIIB (Catalog#90014-C08H; AAL92097.1; Met1-Pro217) and conjugated with APC under optimum conditions, the unreacted APC was removed.
SourceMonoclonal Mouse IgG1 Clone #12
PurificationProtein A
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Concentration5 μl/Test, 0.1 mg/ml
ConjugateAPC
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Cynomolgus CD32 expression on Cynomolgus monocytes. Cells were stained with APC-conjugated anti-CD32. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Image 1 Alt TextCynomolgus CD32b/FCGR2B/Fc gamma RIIB Flow Cytometry (FC) 18489
Image 1 URLSource image

Background Information

Full NameFc fragment of IgG, low affinity IIb, receptor (CD32)
Research Areas
  • Fc Receptors
  • ITIM/ITAM Immunoreceptors and Related Molecules
Related Pathways
  • B Cell Receptor Signaling Pathway

title: The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions.
authors: Juan C Osorio; Patrick Smith; ...; Jeffrey V Ravetch
journal: Cancer cell
date: 2024-01-09
pmid: 37977147
doi: 10.1016/j.ccell.2023.10.007
cited_by_count: 53
techniques: Control; Flow Cytometry; Liposomes; Mouse Assay; Recombinant; Software; Spectrophotometry; Staining
bioz_score: 92

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