Produced in rabbits immunized with E. coli-derived Human FAM169A fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Immunochemical staining of human FAM169A in human testis with rabbit polyclonal antibody at 1:5000 dilution, formalin-fixed paraffin embedded sections.
FAM169A (Family With Sequence Similarity 169 Member A) is located on human chromosome 5q13.3. FAM169A may also be known as SLAP75, soluble lamin-associated protein of 75 kDa, and protein FAM169A. The FAM169A gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog. 200 organisms have orthologs with human gene FAM169A.The FAM169A protein is broadly expressed in brain, testis and other tissues. Structurally, the protein is reported to be 75 kD in mass. FAM169A is associated with some diseases, such as Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant.
References
Roux KJ, et al. (2012) A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. J Cell Biol 196 (6): 801-810.