Anti-GGCT Antibody, Rabbit Polyclonal sinobiological 14366-T60

$143.00
In stock
SKU
14366-T60
Catalog No.SizePrice (USD)
14366-T60-5050 µL$147.96
14366-T60-100100 µL$251.64
14366-T60-200200 µL$355.32

General Information

Product nameAnti-GGCT Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GGCT
ImmunogenRecombinant Human GGCT protein (Catalog#14366-H07E)
PreparationProduced in rabbits immunized with purified, recombinant Human GGCT (rh GGCT; Catalog#14366-H07E; O75223-1; Met1-Leu188). GGCT specific IgG was purified by Human GGCT affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-C7orf24 Antibody; Anti-CRF21 Antibody; Anti-GCTG Antibody; Anti-GGC Antibody; Anti-MGC3077 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Image 1 Alt TextHuman GGCT Immunohistochemistry(IHC) 4142
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Image 2 Alt TextHuman GGCT Immunohistochemistry(IHC) 4143
Image 2 URLSource image
Image 3 DescriptionImmunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Image 3 Alt TextHuman GGCT Immunohistochemistry(IHC) 4144
Image 3 URLSource image
Image 4 DescriptionImmunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Image 4 Alt TextHuman GGCT Immunoprecipitation(IP) 6069
Image 4 URLSource image
Image 5 DescriptionImmunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (1:10000, formalin-fixed paraffin embedded sections).
Image 5 Alt TextHuman GGCT Western blot (WB) 6716
Image 5 URLSource image

Background Information

Full Namegamma-glutamylcyclotransferase
DescriptionGGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
References
  1. Wagner SA. et al., 2011, Mol Cell Proteomics. 10 (10): M111.013284.
  2. Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
  3. Amano T. et al., 2012, J Histochem Cytochem. 60 (1): 76-86.

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