| Catalog No. | Size | Price (USD) |
| 201760-T44-50 | 50 µL | $147.96 |
| 201760-T44-100 | 100 µL | $251.64 |
| 201760-T44-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-alpha Actinin 4/ACTN4 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human alpha Actinin 4/ACTN4 |
| Immunogen | E. coli-derived Human alpha Actinin 4/ACTN4 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human alpha Actinin 4/ACTN4 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ACTININ-4 Antibody; Anti-FSGS Antibody; Anti-FSGS1 Antibody
Image / Experimental Information
| Image 1 Description | Anti-ACTN4 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: MCF-7 Whole Cell Lysate Lane D: Hela Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:105 kDa Observed band size:105 kDa |
| Image 1 Alt Text | Human alpha Actinin 4/ACTN4 Western blot (WB) 29239 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-ACTN4 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: MCF-7 Whole Cell Lysate Lane D: Hela Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:105 kDa Observed band size:105 kDa |
| Image 2 Alt Text | Human alpha Actinin 4/ACTN4 Immunohistochemistry(IHC) 29240 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-ACTN4 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: MCF-7 Whole Cell Lysate Lane D: Hela Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:105 kDa Observed band size:105 kDa |
| Image 3 Alt Text | Human alpha Actinin 4/ACTN4 Immunohistochemistry(IHC) 29241 |
| Image 3 URL | Source image |
| Image 4 Description | Anti-ACTN4 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: MCF-7 Whole Cell Lysate Lane D: Hela Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:105 kDa Observed band size:105 kDa |
| Image 4 Alt Text | Human alpha Actinin 4/ACTN4 Immunoprecipitation(IP) 29242 |
| Image 4 URL | Source image |
Background Information
| Full Name | actinin, alpha 4 |
| Description | Actinin, alpha 4 (ACTN4), a nonmuscle cytoskeleton protein, has been frequently reported to be associated with cell motility and cancer metastasis. Honda et al. have suggested that cytoplasmic ACTN4 increases cell motility and is associated with a high metastatic potential and a poor prognosis of cancer based on their studies on multiple cancer cell lines. Since then, ACTN4 has been reported to be associated with the progression and metastasis of many types of cancer, including breast, colorectal, pancreatic, lung, brain, bladder, and ovarian cancers and salivary gland carcinoma. |
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