Influenza A H3N2 Hemagglutinin / HA Antibody, Rabbit PAb, Antigen Affinity Purified sinobiological 11056-T62

$86.00
In stock
SKU
11056-T62
Catalog No.SizePrice (USD)
11056-T62-2020 µL$88.87
11056-T62-5050 µL$147.96
11056-T62-100100 µL$251.64
11056-T62-200200 µL$355.32

General Information

Product nameInfluenza A H3N2 Hemagglutinin / HA Antibody, Rabbit PAb, Antigen Affinity Purified
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol)
Application notesIHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.)
SpecificityInfluenza A H3N2 (A/Brisbane/10/2007) HA protein Has cross-reactivity in ELISA and WB with H3N2 (A/Darwin/1415/2025) HA trimer Protein (Cat# 41128-V08H) Has cross-reactivity in ELISA with H1N1 (A/Wisconsin/67/2022) HA Trimer Protein (Cat# 40940-V08H2) H1N1 (A/Wisconsin/67/2022) HA Protein (Cat# 40940-V08B) H1N1 (A/Wisconsin/67/2022) HA Protein (Cat# 40940-V08H) H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08B) H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08H) H3N2 (A/Massachusetts/18/2022; A/Thailand/8/2022) HA Protein (Cat# 40992-V08B) H3N2 (A/Massachusetts/18/2022; A/Thailand/8/2022) HA Protein (Cat# 40992-V08H) Influenza B (B/Austria/1359417/2021) HA Protein (Cat# 40862-V08H) Influenza B (B/Austria/1359417/2021) HA Protein (Cat# 40862-V08B)
ImmunogenRecombinant H3N2 (A/Brisbane/10/2007) HA protein (Catalog#11056-V08H)
PreparationProduced in rabbits immunized with purified, recombinant H3N2 (A/Brisbane/10/2007) HA / Hemagglutinin (Catalog#11056-V08H; ABW23353.1; Met 1-Ile 531). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Image / Experimental Information

Image 1 DescriptionAnti-HA rabbit polyclonal antibody at 1:5000 dilution. Sample:Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin / HA Recombinant Protein Lane A: 30ng Lane B: 5ng Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions.
Image 1 Alt TextH3N2 Hemagglutinin/HA Western blot (WB) 30689
Image 1 URLSource image
Image 2 DescriptionAnti-HA rabbit polyclonal antibody at 1:5000 dilution. Sample:Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin / HA Recombinant Protein Lane A: 30ng Lane B: 5ng Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions.
Image 2 Alt TextH3N2 Hemagglutinin/HA Western blot (WB) 44116
Image 2 URLSource image
Image 3 DescriptionAnti-HA rabbit polyclonal antibody at 1:5000 dilution. Sample:Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin / HA Recombinant Protein Lane A: 30ng Lane B: 5ng Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions.
Image 3 Alt TextH3N2 Hemagglutinin/HA Western blot (WB) 49209
Image 3 URLSource image

Background Information

Full NameHemagglutinin
DescriptionThe influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
References
  1. White JM, Hoffman LR, Arevalo JH, et al. Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin. In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.1997
  2. Suzuki Y.Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 2005.
  3. Senne DA, Panigrahy B, Kawaoka Y, et al. Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential. Avian Dis. 1996
  4. Donald J. Benton,Influenza hemagglutinin membrane anchor,PNAS,2018

title: Hypoxia-Enhanced N110 Glycosylation of Hemagglutinin Promotes H3N2 Influenza Virus Fitness by Modulating Receptor Binding and Immune Evasion
authors: Ting Zhang; Yihui Fang; ...; Bumsuk Hahm
journal: Viruses
date: 2026-05-08
pmid: 42198750
doi: 10.3390/v18050547
cited_by_count: 0
bioz_score: 94

title: Isolation, identification, and whole genome sequencing analysis of influenza A virus clinical isolates from Shanghai, China, during 2022-2023.
authors: Muhammad Asif Raza; Bei Shen; ...; Yihong Hu
journal: Virology journal
date: 2026-02-04
pmid: 41639736
doi: 10.1186/s12985-025-03060-7
cited_by_count: 0
bioz_score: 94

title: Identification and characterization of avian-origin H3N2 canine influenza viruses in northern China during 2009-2010.
authors: Yipeng Sun; Shasha Sun; ...; Jinhua Liu
journal: Virology
date: 2013-03-04
pmid: 23063406
doi: 10.1016/j.virol.2012.09.037
cited_by_count: 32
techniques: Generated; Labeling; Virus; Western Blot
bioz_score: 94

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