Influenza A H1N1 Hemagglutinin / HA Antibody, Mouse MAb sinobiological 11684-MM03

$2,071.00
In stock
SKU
11684-MM03
Catalog No.SizePrice (USD)
11684-MM03-11 mL$2,147.61
11684-MM03-2020 µL$118.49
11684-MM03-5050 µL$222.17
11684-MM03-100100 µL$370.28

General Information

Product nameInfluenza A H1N1 Hemagglutinin / HA Antibody, Mouse MAb
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol), ELISA(Det) (FAQ Protocol)
Application notesIHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.)
SpecificityH1N1 (A/Puerto Rico/8/1934) HA Has cross-reactivity in ELISA with H1N1 (A/Puerto Rico/8/1934) HA Protein (Cat# 11684-V08H) Has cross-reactivity in WB with H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08H) H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08B) H3N2 (A/Darwin/6/2021) HA Protein (Cat# 40868-V08H) No cross-reactivity in ELISA with H1N1 (A/BrevigMission/1/1918) HA H1N1 (A/Brisbane/02/2018) HA H1N1 (A/Brisbane/59/2007) HA H1N1 (A/Brisbane/59/2007) HA1 H1N1 (A/California/04/2009) HA Protein (Cat# 11055-V08H) H1N1 (A/California/04/2009) HA1 H1N1 (A/California/07/2009) HA Protein (Cat# 11085-V08B) H1N1 (A/Guangdong-Maonan/SWL1536/2019) / (A/Hawaii/70/2019) HA H1N1 (A/Michigan/45/2015) HA Protein (Cat# 40567-V08H1) H1N1 (A/New Caledonia/20/1999) HA H1N1 (A/Ohio/UR06-0091/2007) HA H1N1 (A/Solomon Islands/3/2006) H1N1 (A/Victoria/4897/2022) HA Protein (Cat# 40938-V08H) H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) HA Protein (Cat# 40787-V08H) H1N1 (A/Wisconsin/67/2022) HA Protein (Cat# 40940-V08H) H1N1 (A/WSN/1933) HA H1N2 (A/swine/Guangxi/13/2006) HA H1N3 (A/duck/NZL/160/1976) HA H3N2 (A/Brisbane/10/2007) HA Protein (Cat# 11056-V08H) H3N2 (A/Cambodia/e0826360/2020) HA H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08H) H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08B) H3N2 (A/Darwin/6/2021) HA Protein (Cat# 40868-V08H) H3N2 (A/Darwin/6/2021) HA Protein (Cat# 40868-V08B) H3N2 (A/Hong Kong/1/1968) HA Protein (Cat# 40116-V08B) H3N2 (A/Hong Kong/2671/2019) HA H3N2 (A/Hong Kong/45/2019) HA H3N2 (A/Hong Kong/4801/2014) HA Protein (Cat# 40555-V08B) H3N2 (A/Kansas/14/2017) HA H3N2 (A/Singapore/INFIMH-16-0019/2016) HA H3N2 (A/Switzerland/9715293/2013) HA H5N1 (A/Anhui/1/2005) HA H5N1 (A/Anhui/1/2005) HA2 H5N1 (A/Indonesia/5/2005) HA Protein (Cat# 11060-V08H2) Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein (Cat# 40862-V08H) Influenza B (B/Austria/1359417/2021)(Victoria lineage) HA Protein (Cat# 40862-V08B) Influenza B (B/Brisbane/60/2008) HA Protein (Cat# 40016-V08B) Influenza B (B/Colorado/06/2017) HA Protein (Cat# 40581-V08H) Influenza B (B/Florida/4/2006) HA Protein (Cat# 11053-V08H) Influenza B (B/PHUKET/3073/2013) HA Protein (Cat# 40498-V08B) Influenza B (B/Washington/02/2019) HA Protein (Cat# 40722-V08H)
ImmunogenRecombinant H1N1 (A/Puerto Rico/8/1934) HA protein (Catalog#11684-V08H)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant H1N1 (A/Puerto Rico/8/1934) HA (Catalog#11684-V08H; ABD77675.1; Met 1-Gln 528). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG1 Clone #2F1A7
PurificationProtein A
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Image / Experimental Information

Image 1 DescriptionAnti-HA mouse monoclonal antibody at 1:1000 dilution. Sample: Recombinant Protein 10 ng Lane A: H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08H) Lane B: H3N2 (A/Darwin/9/2021) HA Protein (Cat# 40859-V08B) Lane C: H3N2 (A/Darwin/6/2021) HA Protein (Cat# 40868-V08H) Secondary Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions.
Image 1 Alt TextH1N1 Hemagglutinin/HA Western blot (WB) 34360
Image 1 URLSource image

Background Information

Full NameHemagglutinin
DescriptionThe influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
References
  1. White JM, Hoffman LR, Arevalo JH, et al. Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin. In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.1997
  2. Suzuki Y.Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 2005.
  3. Senne DA, Panigrahy B, Kawaoka Y, et al. Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential. Avian Dis. 1996
  4. Donald J. Benton,Influenza hemagglutinin membrane anchor,PNAS,2018

title: Neuraminidase of influenza A viruses induces global desialylation of host cells via its intracellular function
authors: Daiki Kobayashi; Takahiro Hiono; ...; Robert Paul de Vries
journal: Microbiology Spectrum
date: 2026-04-01
pmid: 41705853
cited_by_count: 0
techniques: Bioprocessing
bioz_score: 95

title: A Dynamic Oligomerization Network Coordinates Hemagglutinin-Mediated Membrane Fusion on Influenza Virions
authors: Chen Yong; Zhang Zheyuan; ...; Li Sai
journal: bioRxiv
date: 2026-03-25
doi: 10.64898/2026.03.23.713829
cited_by_count: 0
techniques: Control; Expressing; Incubation; Plasmid Preparation; Recombinant; Transfection; Western Blot
bioz_score: 95

title: Loop structure in poly(A) tail of mRNA vaccine enhances antigen translation efficiency and mRNA stability.
authors: Ayoung Oh; Seonghyun Lee; ...; Jae-Hwan Nam
journal: NPJ vaccines
date: 2025-11-18
pmid: 41249784
cited_by_count: 0
techniques: BIA-KA; Incubation; Protein Extraction; Transfection; Western Blot
bioz_score: 95

title: Restriction of influenza A virus replication by host DCAF7-CRL4B axis.
authors: Lei Yu; Yong Jiang; ...; Ke Lan
journal: Journal of virology
date: 2025-03-27
pmid: 40145735
cited_by_count: 1
techniques: Immunofluorescence; Luciferase; Recombinant; Reporter Assay; Western Blot
bioz_score: 95

title: Light-responsive bifunctional crosslinker enables facile preparation of antifouling sensor array for immunodetection of viral antigens
authors: Shijie Sun; Yancao Chen; ...; Xiao-Bing Zhang
journal: Sensors and Actuators B: Chemical
date: 2025-01-01
doi: 10.1016/j.snb.2024.136570
cited_by_count: 0
bioz_score: 95

title: CXCL13 promotes broad immune responses induced by circular RNA vaccines
authors: Jiawu Wan; Caiqian Wang; ...; Ling Zhao
journal: Proceedings of the National Academy of Sciences of the United States of America
date: 2024-10-22
pmid: 39436660
doi: 10.1073/pnas.2406434121
pmcid: 11536096
cited_by_count: 19
techniques: Blocking Assay; Enzyme-linked Immunosorbent Assay; Incubation; Lyophilization; Recombinant; Variant Assay
bioz_score: 95

title: iGATE analysis improves the interpretability of single-cell immune landscape of influenza infection
authors: Brett D. Hill; Andrew J. Zak; ...; Fei Wen
journal: JCI insight
date: 2024-05-30
pmid: 38814732
doi: 10.1172/jci.insight.172140
pmcid: 11383363
cited_by_count: 1
techniques: Infection; Plasmid Preparation
bioz_score: 95

title: C1QTNF5 is a novel attachment factor that facilitates the entry of influenza A virus.
authors: Lei Yu; Xinjin Liu; ...; Ke Lan
journal: Virologica Sinica
date: 2024-01-19
pmid: 38246238
doi: 10.1016/j.virs.2024.01.003
cited_by_count: 1
techniques: Clone Assay; Expressing; Luciferase; Membrane; Reporter Assay; Transfection; Virus
bioz_score: 95

title: Optimizing virus inactivation methods for molecular detection techniques: Implications for viral protein and RNA measurements.
authors: Takema Hasegawa; Sachie Shibayama; ...; Megumi Kato
journal: Journal of virological methods
date: 2023-09-21
pmid: 37625621
doi: 10.1016/j.jviromet.2023.114801
cited_by_count: 1
techniques: Cell Culture; Virus
bioz_score: 95

title: Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles.
authors: Joanne Haney; Swetha Vijayakrishnan; ...; Pablo R Murcia
journal: Nature Microbiology
date: 2022-10-31
pmid: 36280786
doi: 10.1038/s41564-022-01242-5
cited_by_count: 47
techniques: Virus
bioz_score: 95

title: C-Terminally tagged NA in replication-competent influenza A viruses reveals differences in glycan profiles between NA and HA
authors: Takahiro Hiono; Atsushi Kuno
journal: The Analyst
date: 2020-01-01
doi: 10.1039/d0an00770f
cited_by_count: 0
bioz_score: 95

title: Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses.
authors: Takahiro Hiono; Atsushi Matsuda; ...; Atsushi Kuno
journal: Virology
date: 2019-03-05
pmid: 30503907
doi: 10.1016/j.virol.2018.11.010
cited_by_count: 17
bioz_score: 95

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