| Catalog No. | Size | Price (USD) |
| 15307-RP01-100 | 100 µL | $147.96 |
| 15307-RP01-200 | 200 µL | $251.64 |
| 15307-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-AKR1C4 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human AKR1C4 |
| Immunogen | Recombinant Human AKR1C4 / 3-alpha-HSD1 Protein (Catalog#15307-H07E) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human AKR1C4 / 3-alpha-HSD1 (rh AKR1C4 / 3-alpha-HSD1; Catalog#15307-H07E; AAH20744.1; Met1-Tyr323). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-3-alpha-HSD Antibody; Anti-C11 Antibody; Anti-CDR Antibody; Anti-CHDR Antibody; Anti-DD-4 Antibody; Anti-DD4 Antibody; Anti-HAKRA Antibody; Anti-MGC22581 Antibody
Background Information
| Full Name | aldo-keto reductase family 1, member C4 |
| Description | Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, and xenobiotic metabolism. |
