| Catalog No. | Size | Price (USD) |
| 12177-MM35T-A-25 | 25 Tests | $133.30 |
| 12177-MM35T-A-100 | 100 Tests | $325.84 |
General Information
| Product name | Anti-Alpha-fetoprotein Antibody (APC), Mouse Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Alpha-fetoprotein |
| Immunogen | Recombinant Human AFP / alpha-fetoprotein protein (Catalog#12177-H08H) |
| Preparation | This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Source | Monoclonal Mouse IgG1 Clone #35 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | APC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! |
Synonyms: Anti-AFPD Antibody; Anti-FETA Antibody; Anti-HPAFP Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human AFP expression on HepG2 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with APC-conjugated anti-Human AFP. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Image 1 Alt Text | Human Alpha-fetoprotein/AFP Flow Cytometry (FC) 17445 |
| Image 1 URL | Source image |
Background Information
| Full Name | alpha-fetoprotein |
| Description | Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month, when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC), teratoblastomas, and neural tube defect (NTD). |
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