| Catalog No. | Size | Price (USD) |
| 100355-T32-50 | 50 µL | $147.96 |
| 100355-T32-100 | 100 µL | $251.64 |
| 100355-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ARID3B Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ARID3B |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the human ARID3B |
| Preparation | Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human ARID3B , and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BDP Antibody; Anti-DRIL2 Antibody
Image / Experimental Information
| Image 1 Description | Anti-ARID3B rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:61 kDa Observed band size:61 kDa (We are unsure as to the identity of these extra bands.) |
| Image 1 Alt Text | Human ARID3B Western blot (WB) 6465 |
| Image 1 URL | Source image |
Background Information
| Full Name | AT-rich interaction domain 3B |
| Description | ARID3B, a member of the AT-rich interaction domain (ARID) family of proteins, plays an essential role in the survival of neural crest during embryogenesis. ARID3B seems to play a key role in the malignant transformation of neuroblastoma and may serve not only as a marker of malignancy but also as a potential target for cancer therapy of stage IV neuroblastoma for which there is currently no effective treatment available. ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. ARID3B has different patterns in normal tissues translate into different roles for ARID3B in carcinomas. ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging role of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples and breast cancer-derived cell lines. ARID3B regulation of direct target genes in the Wnt pathway promotes adhesion of ovarian cancer cells. ARID3A and ARID3B are transcriptional targets of p53, ARID3B play a key role in the expression of pro-apoptotic p53-target genes and apoptosis. |
title: Serine 89 Phosphorylation Controls Nuclear Localization and Transcriptional Activity of ARID3B
authors: Micneya Landeros-Rodriguez; Krishna Ailiani; ...; Karen D. Cowden Dahl
journal: Cells
date: 2026-03-30
doi: 10.3390/cells15070612
cited_by_count: 0
techniques: Generated; Staining; Western Blot
bioz_score: 94
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