| Catalog No. | Size | Price (USD) |
| 12432-R004-50 | 50 µL | $177.58 |
| 12432-R004-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-C1D Antibody, Rabbit Monoclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human C1D |
| Immunogen | Recombinant Human C1D protein (Catalog#12432-H09E) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human C1D (rh C1D; Catalog#12432-H09E; Q13901; Met1-Ser141). |
| Source | Monoclonal Rabbit IgG Clone #004 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-hC1D Antibody; Anti-LRP1 Antibody; Anti-Rrp47 Antibody; Anti-SUN-CoR Antibody; Anti-SUNCOR Antibody
Image / Experimental Information
| Image 1 Description | Anti-C1D rabbit monoclonal antibody at 1:500 dilution Lane A: Hela Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:16 kDa Observed band size:16 kDa |
| Image 1 Alt Text | Human C1D Western blot (WB) 13489 |
| Image 1 URL | Source image |
Background Information
| Full Name | C1D nuclear receptor corepressor |
| Description | C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner. |
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