| Catalog No. | Size | Price (USD) |
| 10107-RP01-100 | 100 µL | $147.96 |
| 10107-RP01-200 | 200 µL | $251.64 |
| 10107-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-Carbonic Anhydrase IX/CA9 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Carbonic Anhydrase IX/CA9 |
| Immunogen | Recombinant Human CAIX protein (Catalog#10107-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human carbonic anhydrase IX (rh CAIX; Catalog#10107-H08H; NP_001207.2; Met 1-Asp 414). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CAIX Antibody; Anti-G250 Antibody; Anti-MN Antibody
Background Information
| Full Name | carbonic anhydrase IX |
| Description | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers. |
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