Anti-CaMKII alpha/CAMK2A Antibody, Rabbit Polyclonal sinobiological 100866-T08

$143.00
In stock
SKU
100866-T08
Catalog No.SizePrice (USD)
100866-T08-5050 µL$147.96
100866-T08-100100 µL$251.64
100866-T08-200200 µL$355.32

General Information

Product nameAnti-CaMKII alpha/CAMK2A Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Mouse, Rat (Species predicted to react based on 100% sequence homology)
ImmunogenA synthetic peptide corresponding to the C-terminus of the Human CAMK2A
PreparationProduced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human CAMK2A, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CAMKA Antibody; Anti-CaMKIIalpha Antibody; Anti-CaMKIINalpha Antibody; Anti-CaMKIIα Antibody; Anti-KIAA0968 Antibody; Anti-MRD53 Antibody; Anti-MRT63 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human CAMK2A in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Image 1 Alt TextHuman CAMK2A Immunohistochemistry(IHC) 4605
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human CAMK2A in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Image 2 Alt TextHuman CAMK2A Immunohistochemistry(IHC) 4606
Image 2 URLSource image

Background Information

Full Namecalcium/calmodulin-dependent protein kinase II alpha
DescriptionCa /calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca / calmodulin-dependent protein kinase subfamily. CaM kinase Ⅱ is thought to be an important mediator of learning and memory and is also necessary for Ca homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.
Research Areas
  • Calcium-binding Proteins and Related Molecules
Related Pathways
  • EGFR Signaling Pathway
  • Non-Canonical Wnt Pathway
  • B Cell Receptor Signaling Pathway
  • G Protein-coupled Receptors Signaling
References
  1. Lin CR, et al. (1987). Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A. 84 (16): 5962-6.
  2. Walikonis RS, et al. (2001) Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. J Neurosci. 21 (2): 423-33.
  3. Gardoni F, et al. (2003) CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction. J Biol Chem. 278 (45): 44745-52.

title: Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration
authors: Tao Wang; Fei Ding; Kai Sun
journal: Frontiers in Genetics
date: 2025-08-14
doi: 10.3389/fgene.2025.1527907
cited_by_count: 0
techniques: Blocking Assay; Expressing; Immunohistochemistry; Incubation; Software; Staining
bioz_score: 93

title: Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification.
authors: Kai Sun; Cheng Huang; ...; Zhan-Xiong Luo
journal: World Journal of Surgical Oncology
date: 2022-10-19
pmid: 36253777
doi: 10.1186/s12957-022-02802-z
cited_by_count: 6
techniques: Expressing; Immunohistochemical staining; Immunohistochemistry; Mutagenesis; Quantitative Proteomics; Software; Staining
bioz_score: 93

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