| Catalog No. | Size | Price (USD) |
| 10805-MM05-50 | 50 µL | $147.96 |
| 10805-MM05-100 | 100 µL | $251.64 |
| 10805-MM05-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD10/Neprilysin Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD10/Neprilysin No cross-reactivity in ELISA with Human cell lysate (293 cell line) |
| Immunogen | Recombinant Human CD10 / Neprilysin / MME protein (Catalog#10805-H07H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD10 / Neprilysin / MME (rh CD10 / Neprilysin / MME; Catalog#10805-H07H; NP_000893.2; Tyr 52-Trp 750). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG2a Clone #05 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CALLA Antibody; Anti-CD10 Antibody; Anti-CMT2T Antibody; Anti-EPN Antibody; Anti-NEP Antibody; Anti-SCA43 Antibody; Anti-SFE Antibody
Background Information
| Full Name | membrane metallo-endopeptidase |
| Description | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. The cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had the function to degrade some small secreted peptides such as the amyloid beta-peptide. It exists as a membrane-bound protein and has a high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes. |
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