| Catalog No. | Size | Price (USD) |
| 12191-MM09-50 | 50 µL | $147.96 |
| 12191-MM09-100 | 100 µL | $251.64 |
| 12191-MM09-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD160 Antibody, Mouse Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD160 |
| Immunogen | Recombinant Human CD160 / NK1 / BY55 Protein (Catalog#12191-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD160 / NK1 / BY55 (rh CD160 / NK1 / BY55; Catalog#12191-H08H; NP_008984.1; Met1-Leu158). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG2b Clone #09 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BY55 Antibody; Anti-NK1 Antibody; Anti-NK28 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human CD160 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD160, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Image 1 Alt Text | Human CD160/NK1/BY55 Flow Cytometry (FC) 5307 |
| Image 1 URL | Source image |
Background Information
| Full Name | CD160 molecule |
| Description | CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness. |
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