Anti-CD38 Antibody (PerCP), Mouse Monoclonal sinobiological 10818-MM27-C

$129.00
In stock
SKU
10818-MM27-C
Catalog No.SizePrice (USD)
10818-MM27-C-2525 Tests$133.30
10818-MM27-C-100100 Tests$414.71

General Information

Product nameAnti-CD38 Antibody (PerCP), Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD38
ImmunogenRecombinant Human CD38/ADPRC1 Protein (Catalog#10818-H08H)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD38/ADPRC1 (rh CD38/ADPRC1; Catalog#10818-H08H; NP_001766.2; Val43-Ile300) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed.
SourceMonoclonal Mouse IgG1 Clone #27
PurificationProtein A
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Concentration5 μl/Test, 0.1 mg/ml
ConjugatePerCP
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Synonyms: Anti-ADPRC 1 Antibody; Anti-ADPRC1 Antibody; Anti-cADPR1 Antibody

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Human CD38 expression on human whole blood lymphocytes. Cells were stained with PerCP-conjugated anti-Human CD38. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Image 1 Alt TextHuman CD38/ADPRC1 Flow Cytometry (FC) 18345
Image 1 URLSource image

Background Information

Full NameCD38 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4 , CD8 , B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.
Research Areas
  • Cancer Drug Targets
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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